ZFIN Figure: Ciura et al., 2013, Fig. 3

ZFIN ID: ZDB-FIG-140620-6

ZFIN ID: ZDB-FIG-140620-6

Ciura et al., 2013 - Loss of function of C9orf72 causes motor deficits in a zebrafish model of Amyotrophic Lateral Sclerosis. Annals of neurology 74(2):180-187 Full text @ Ann. Neurol.

ADDITIONAL FIGURES

EXPRESSION / LABELING:

Gene:	zgc:100846
Fish:	mitfa^w2/w2
Anatomical Terms:	forebrain hindbrain spinal cord telencephalon
Stage:	Prim-5

PHENOTYPE:

Fish:	AB + MO1-zgc:100846 AB + MO2-zgc:100846
Knockdown Reagents:	MO1-zgc:100846 MO2-zgc:100846
Observed In:	motor neuron axon thigmotaxis whole organism
Stage:	Long-pec

Fig. 3 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details

Gene	Fish	Conditions	Stage	Anatomy	Assay
zgc:100846	mitfa^w2/w2	standard conditions	Prim-5	forebrain	ISH
			Prim-5	hindbrain	ISH
			Prim-5	spinal cord	ISH
			Prim-5	telencephalon	ISH

Antibody Labeling Details No data available

Phenotype Details

Fish	Conditions	Stage	Phenotype
AB + MO1-zgc:100846	standard conditions	Long-pec	motor neuron axon branchiness, abnormal
		Long-pec	motor neuron axon decreased length, abnormal
		Long-pec	thigmotaxis disrupted, abnormal
		Long-pec	whole organism dead, abnormal
AB + MO2-zgc:100846	standard conditions	Long-pec	motor neuron axon branchiness, abnormal
		Long-pec	motor neuron axon decreased length, abnormal
		Long-pec	thigmotaxis disrupted, abnormal
		Long-pec	whole organism dead, abnormal

Full text @ Ann. Neurol.