FIGURE

Fig. 5

ID
ZDB-FIG-131218-3
Publication
Phillips et al., 2013 - The cone-dominant retina and the inner ear of zebrafish express the ortholog of CLRN1, the causative gene of human Usher syndrome type 3A
Other Figures
All Figure Page
Back to All Figure Page
Fig. 5

Clarin-1 localizes at interfaces between photoreceptor inner segments in the adult retina. (A-C) Cross (A and B) and transverse (C) sections through adult retinas show Clarin-1 localization partially overlapping with glial cells labeled with Glutamine Synthetase (GS) at the OLM (arrowhead). Enrichment of Clarin-1 is also noted in the subapical region (SAR) and between all cone inner segments in the outer retina. The silhouettes of the four cone subtypes are outlined in white in A, D and G and the mosaic cone arrangement is labeled in C, F and I. (D-I) Cross (D-E, G-H) and transverse (F, I) sections of adult retinas labeled with Crb2a (D-F) and Crb2b (G-I) antibodies recapitulate results published by Zou et al., 2012, and provide points of reference for the Clarin-1 (A-C) localization pattern at lateral cone interfaces. Abbreviations: OLM: outer limiting membrane; G: green opsin cone, R: red opsin cone; B: blue opsin cone; SAR (subapical region) U: UV opsin cone. Scale bars: 10 µm.

Expression Data
Gene:
Antibodies:
Fish:
Anatomical Terms:
Stage: Adult

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Gene expression patterns : GEP, 13(8), Phillips, J.B., Västinsalo, H., Wegner, J., Clément, A., Sankila, E.M., and Westerfield, M., The cone-dominant retina and the inner ear of zebrafish express the ortholog of CLRN1, the causative gene of human Usher syndrome type 3A, 473-81, Copyright (2013) with permission from Elsevier. Full text @ Gene Expr. Patterns