Gene

clrn1

ID
ZDB-GENE-040718-420
Name
clarin 1
Symbol
clrn1 Nomenclature History
Previous Names
  • zgc:91933
Type
protein_coding_gene
Location
Chr: 15 Mapping Details/Browsers
Description
Acts upstream of or within several processes, including plasma membrane bounded cell projection organization; sensory perception of sound; and synaptic vesicle recycling via endosome. Located in ciliary transition zone and stereocilium bundle. Is expressed in auditory epithelial support cell; brain; receptor cell (sensu Animalia); and sensory system. Used to study Usher syndrome. Human ortholog(s) of this gene implicated in Usher syndrome type 3A and retinitis pigmentosa 61. Orthologous to human CLRN1 (clarin 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
11 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
11 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With clrn1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
retinitis pigmentosa 61 Alliance Retinitis pigmentosa 61 614180
Usher syndrome type 3A Alliance Usher syndrome, type 3A 276902
Associated With clrn1 Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR026748 Clarin
Domain Details Per Protein
Protein Length Clarin
UniProtKB:Q6DGA8 232
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab2-clrn1 polyclonal Rabbit
  • IHC
Proteintech
2
Ab1-clrn1 polyclonal Rabbit
  • IHC
  • WB
Novus Biologicals, LLC
4
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations