FIGURE

Fig. S8

ID

ZDB-FIG-130429-44

Publication

Hegarty et al., 2013 - UBIAD1-mediated vitamin K2 synthesis is required for vascular endothelial cell survival and development

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Fig. S8

Warfarin treatment of zebrafish at 24 hpf results in cranial endothelial cell apoptosis. (A-D) Confocal sections of 48 and 72 hpf Tg(kdrl:gfp) DMSO (control)- and warfarin-treated zebrafish that were TUNEL stained (red) reveal that (B,D) warfarin-treated endothelial cells exhibit increased apoptosis (yellow arrows) when compared with (A,C) control endothelial cells. (E,F) The number of apoptotic cells observed per high-power field for each condition. Mean+s.e.m. Student’s t-test, *P<0.05 (n=15 reh and wild-type zebrafish).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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