FIGURE

Fig. 5

ID

ZDB-FIG-120126-38

Publication

Schepis et al., 2012 - αE-catenin regulates cell-cell adhesion and membrane blebbing during zebrafish epiboly

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Fig. 5

αE-catenin depletion triggers protracted bleb-like protrusions. (A-C) Selected confocal images from time-lapse movies at the most external epiblast layer of the animal pole at 50% epiboly. Membranes are labeled with mbGFP. Arrows indicate membrane blebs. Scale bars: 8 μm. (D) Percentage of cells exhibiting bleb-like protrusions over 5 minutes. n=12 embryos. ^#P<10^–5 control versus rescue, ^*P<10^–5 control versus morphant. Error bars indicate s.e.m. (E) Average number of blebs per cell over 5 minutes. n=12 embryos. ^#P<10^–8 control versus rescue, ^*P<10^–8 control versus morphant. Error bars indicate s.e.m.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO1-ctnna1 WT + MO3-cdh1
Knockdown Reagents:	MO1-ctnna1 MO3-cdh1
Observed In:	DEL plasma membrane
Stage:	50%-epiboly

Phenotype Detail

Acknowledgments

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