ZFIN ID: ZDB-FIG-111214-34
Ma et al., 2011 - Characterization of a Weak Allele of Zebrafish cloche Mutant. PLoS One   6(11):e27540 Full text @ PLoS One
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Gene:
Fish:
Anatomical Term:
Stage: Protruding-mouth
PHENOTYPE:
Fish:
Observed In:
Stage: Protruding-mouth

Fig. 5 Analysis of the origin of definitive myeloid cells in clo172 mutant.

(A, B) lyc expression pattern at 3 dpf runx1/clo172 double mutant (A). WISH of lyc expression in siblings (A–i), clo172 mutant (A–ii), clo172 (-/-) runx1 (+/-) w84x (A-iii), double homozygous mutant (A–iv). Histogram of lyc+ cells number (means) in siblings(B, purple column), clo172 mutant (B, green column), clo172 (-/-) runx1 (+/-)w84x (B, pink column) and double homozygous mutant (B, blue column). There are significant differences between double mutant and other groups (*p<0.05), but no difference between clo172 mutant and clo172 (-/-) runx1 (+/-) w84x group (p>0.05). The corresponding case numbers were shown by n in column.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
lclat1 WT standard conditions Protruding-mouth hematopoietic stem cell ISH
npas4lsm0/sm0 standard conditions Protruding-mouth hematopoietic stem cell ISH
npas4lsm0/sm0; runx1hg1/+ standard conditions Protruding-mouth hematopoietic stem cell ISH
npas4lsm0/sm0; runx1hg1/hg1 standard conditions Protruding-mouth hematopoietic stem cell ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
npas4lsm0/sm0 standard conditions Protruding-mouth definitive hemopoiesis disrupted, abnormal
Protruding-mouth hematopoietic stem cell decreased amount, abnormal
npas4lsm0/sm0; runx1hg1/+ standard conditions Protruding-mouth definitive hemopoiesis disrupted, abnormal
Protruding-mouth hematopoietic stem cell decreased amount, abnormal
npas4lsm0/sm0; runx1hg1/hg1 standard conditions Protruding-mouth definitive hemopoiesis disrupted, abnormal
Protruding-mouth hematopoietic stem cell decreased amount, abnormal
Acknowledgments:
ZFIN wishes to thank the journal PLoS One for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ PLoS One