ZFIN ID: ZDB-GENE-081211-2
Gene Name: lysocardiolipin acyltransferase 1
Gene Symbol: lclat1    Nomenclature History

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Previous Names: lycat (1), wu:fj17g04, zgc:77380

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 13 Mapping Details/Browsers
Description: Predicted to have 1-acylglycerol-3-phosphate O-acyltransferase activity. Involved in endothelial cell development and hemangioblast cell differentiation. Predicted to localize to endoplasmic reticulum. Is expressed in hematopoietic stem cell. Orthologous to human LCLAT1 (lysocardiolipin acyltransferase 1).
Genome Resources: Alliance (1),  Gene:406554 (1),  Ensembl(GRCz11):ENSDARG00000103320 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
CRISPR1-lclat1
1
CRISPR2-lclat1
1
MO1-lclat1 N/A 3
MO2-lclat1 N/A 2
MO3-lclat1 N/A 3
DISEASE ASSOCIATED WITH lclat1 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH lclat1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process embryonic hemopoiesis (more)
Cellular Component endoplasmic reticulum (more)
Molecular Function 1-acylglycerol-3-phosphate O-acyltransferase activity (more)
GO Terms (all 16)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS No data available
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM lclat1 No data available
MARKER RELATIONSHIPS
lclat1 Encodes: [EST] fj17g04 (1)
[cDNA] MGC:77380 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_213270 (1)
Polypeptide UniProtKB:Q6NYV8 (1) 388 aa
Sequence Information (all 10)
ORTHOLOGY for lclat1 ( Chr: 13 )
CITATIONS (125)