FIGURE

Fig. 4

ID

ZDB-FIG-091221-20

Publication

Alexa et al., 2009 - Maternal and zygotic aldh1a2 activity is required for pancreas development in zebrafish

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Fig. 4

aldh1a2^um22 and aldh1a2ⁱ²⁶ mutant embryos retain some endoderm gene expression at 48 and 72 hpf.

DMSO treated wild type embryos (A, E, I, M, Q), DEAB-treated wild type embryos (B, F, J, N, R), embryos from an incross of aldh1a2^um22 heterozygotes (C, G, K, O, S) and embryos from an incross of aldh1a2ⁱ²⁶ heterozygotes (D, H, L, P, T) were assayed for expression of pdx1 at 48 hpf (A–D), sid4 at 48 hpf (E–H), carbA at 72 hpf (I–L), ifabp at 72 hpf (M–P) and transf at 72 hpf (Q–T). Gene expression is observed in the intestine (open arrows), liver (black arrowheads) and pancreas (black arrows). Embryos are in dorsal view with anterior to the left. See Table 2 for quantification.

Expression Data

Genes:	cpa5 fabp2 pdx1 sid4 tfa
Fish:	WT aldh1a2^i26/i26 aldh1a2^um22/um22
Condition:	chemical treatment: 4-(diethylamino)benzaldehyde
Anatomical Terms:	intestine liver pancreas
Stage Range:	Long-pec to Protruding-mouth

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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