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General Information
ZIRC
ZFIN ID: ZDB-GENE-990415-122
Gene Name: pancreatic and duodenal homeobox 1
Gene Symbol: pdx1
Sequence Ontology ID : SO:0001217

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Attributions

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Previous Names: pdx-1 (1), ipf1 (1), pancreatic and duodenal homeobox gene 1, zgc:100874

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(Including Attributions)
Location: Chr: 24 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have DNA-binding transcription factor activity and RNA polymerase II proximal promoter sequence-specific DNA binding activity. Involved in determination of left/right symmetry; endocrine  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa12 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa280 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa3263 Point Mutation Unknown Premature Stop ENU
    sa37883 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    DISEASE ASSOCIATED WITH pdx1 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    maturity-onset diabetes of the young type 4 MODY, type IV 606392
    pancreatic agenesis Pancreatic agenesis 1 260370
    type 2 diabetes mellitus {Diabetes mellitus, type II, susceptibility to} 125853
    DISEASE ASSOCIATED WITH pdx1 VIA EXPERIMENTAL MODELS
    Human Disease Fish Conditions Citations
    diabetes mellitus pdx1sa280/sa280 standard conditions Kimmel et al., 2015
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process endocrine pancreas development (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 15)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA pdx1-201 (1) 1117
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIES
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM pdx1
    MARKER RELATIONSHIPS
    pdx1 Contained in: [BAC] CH211-140B10 (1) (order this)
    pdx1 Encodes: [EST] eu283 (1)
    [cDNA] MGC:100874 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131443 (1) 1140 bp
    Genomic GenBank:BX571696 (1) 171175 bp
    Select Tool
    Polypeptide UniProtKB:F1RBA3 (1) 246 aa
    Sequence Clusters UniGene:75810 (1)
    Sequence Information (all 15)
    ORTHOLOGY for pdx1 ( Chr: 24 )
    CITATIONS (137)