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ZFIN ID: ZDB-FIG-090817-41
Huang et al., 2009 - Collagen IX is Required for the Integrity of Collagen II Fibrils and the Regulation of Vascular Plexus Formation in Zebrafish Caudal Fins. Developmental Biology   332(2):360-370 Full text @ Dev. Biol.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Gene:
Antibody:
Fish:
Anatomical Terms:
Stage: Days 14-20
PHENOTYPE:
Fish:
Observed In:
Stage: Days 14-20

Fig. 8 Independent developmental relationship between blood vessels, sensory axons, and the epidermis in a zebrafish caudal fin. (A) A wild-type (WT) fin stained with the Zn8 monoclonal antibody showing the sensory neuronal pattern in the fin. A single axon was found to extend along each fin ray (arrows). (B) In the prp mutant, the sensory axons maintained their ray pattern (arrows) and did not seem to be associated with the vascular plexus pattern. (C) A WT young fin stained with Zn8 and photographed with the focus on the epidermis showing that the epidermis formed a nice fin ray pattern (arrows). (D) A prp young fin showing that the epidermal pattern appeared relatively normal (arrows).

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
EGFP y1Tg standard conditions Days 14-20 caudal fin vasculature IHC
Antibody Labeling Details
Antibody Assay Fish Conditions Stage Anatomy
zn-8 IHC col22a1j131/j131; y1Tg/y1Tg standard conditions Days 14-20 caudal fin axon
IHC Days 14-20 sensory neuron axon
IHC y1Tg standard conditions Days 14-20 caudal fin axon
IHC Days 14-20 sensory neuron axon
Phenotype Details
Fish Conditions Stage Phenotype
col22a1j131/j131; y1Tg/y1Tg standard conditions Days 14-20 caudal fin interray vessel disorganized, abnormal
Days 14-20 caudal fin lepidotrichium malformed, abnormal
Days 14-20 caudal fin morphogenesis disrupted, abnormal
Acknowledgments:
ZFIN wishes to thank the journal Developmental Biology for permission to reproduce figures from this article. Please note that this material may be protected by copyright.

Reprinted from Developmental Biology, 332(2), Huang, C.C., Wang, T.C., Lin, B.H., Wang, Y.W., Johnson, S.L., and Yu, J., Collagen IX is Required for the Integrity of Collagen II Fibrils and the Regulation of Vascular Plexus Formation in Zebrafish Caudal Fins, 360-370, Copyright (2009) with permission from Elsevier. Full text @ Dev. Biol.