FIGURE

Fig. S4

ID
ZDB-FIG-090602-23
Publication
Arduini et al., 2009 - Genetic ablation of neural crest cell diversification
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Fig. S4

The neural plate border develops independent of foxd3 and tfap2a function. (A) pax3 expression at the 3 somite stage, dorsal views with anterior to the top. paired homeobox 3 (pax3) is expressed at the edge of the developing neural plate, and is required for induction of NC-specific gene expression. pax3 is robustly expressed in foxd3zdf10;tfap2alow double mutants, as well as in foxd3zdf10 and tfap2alow single mutant embryos. (B) msxb expression at the 3 somite stage, dorsal views with anterior to the top. msxb expression is required for proper size and positioning of the neural plate border. msxb expression is normal in foxd3zdf10;tfap2alow double mutant, foxd3zdf10 single mutant and tfap2alow single mutant embryos compared with wild-type siblings. (C) huC expression in 6 somite stage embryos. At this stage, primary motor neurons (more medial cells) and Rohon-Beard sensory neurons (bilateral stripes of cells just lateral to primary motorneurons) express huC. Both neuronal populations develop normally in both single mutants, as well as in double mutants.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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