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General Information
ZIRC
ZFIN ID: ZDB-FIG-080225-1
Hanai et al., 2007 - The muscle-specific ubiquitin ligase atrogin-1/MAFbx mediates statin-induced muscle toxicity. J. Clin. Invest.   117(12):3940-3951 Full text @ J. Clin. Invest.
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Knockdown Reagents:
Observed In:
Stage: Prim-15

Fig. 6 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression DetailsNo data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT + MO1-hmgcra + MO2-fbxo32 standard conditions Prim-15 muscle morphology, abnormal
Prim-15 myotome skeletal muscle cell morphology, abnormal
Prim-15 skeletal muscle tissue development disrupted, abnormal
WT + MO1-hmgcra + MO2-fbxo32 + MO2-hmgcra standard conditions Prim-15 muscle morphology, normal
WT + MO1-hmgcra + MO2-hmgcra standard conditions Prim-15 muscle morphology, abnormal
Prim-15 myotome skeletal muscle cell morphology, abnormal
Prim-15 skeletal muscle tissue development disrupted, abnormal
Prim-15 somite border morphology, abnormal
WT + MO2-fbxo32 + MO2-hmgcra standard conditions Prim-15 muscle morphology, abnormal
Prim-15 myotome skeletal muscle cell morphology, abnormal
Prim-15 skeletal muscle tissue development disrupted, abnormal
Full text @ J. Clin. Invest.