ZFIN Figure: Dong et al., 2007, Fig. 3

ZFIN ID: ZDB-FIG-080109-3

ZFIN ID: ZDB-FIG-080109-3

Dong et al., 2007 - Fgf10 regulates hepatopancreatic ductal system patterning and differentiation. Nature Genetics 39(3):397-402 Full text @ Nat. Genet.

ADDITIONAL FIGURES

EXPRESSION / LABELING:

Genes:	DsRed GFP hnf4a prox1a
Antibodies:	Ab-2F11 ab1-hnf4a Ab3-prox1
Fish:	WT fgf10a^tbvbo/tbvbo gz15Tg fgf10a^tbvbo/tbvbo; gz15Tg
Anatomical Terms:	endocrine pancreas hepatic duct intestine liver pancreatic duct
Stage Range:	Pec-fin to Day 4

PHENOTYPE:

Fish:	fgf10a^tbvbo/tbvbo
Observed In:	hepatocyte
Stage:	Day 4

Fig. 3 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details

Gene	Antibody	Fish	Conditions	Stage	Anatomy	Assay
DsRed		fgf10a^tbvbo/tbvbo; gz15Tg	standard conditions	Day 4	endocrine pancreas	IFL
				Day 4	liver	IFL
		gz15Tg	standard conditions	Day 4	liver	IFL
GFP		fgf10a^tbvbo/tbvbo; gz15Tg	standard conditions	Day 4	endocrine pancreas	IFL
		gz15Tg	standard conditions	Day 4	endocrine pancreas	IFL
hnf4a	ab1-hnf4a	WT	standard conditions	Protruding-mouth	intestine	IHC
	ab1-hnf4a	fgf10a^tbvbo/tbvbo	standard conditions	Protruding-mouth	intestine	IHC
prox1a	Ab3-prox1	WT	standard conditions	Pec-fin	endocrine pancreas	IHC
	Ab3-prox1			Pec-fin	liver	IHC
	Ab3-prox1			Protruding-mouth	endocrine pancreas	IHC
	Ab3-prox1			Protruding-mouth	liver	IHC
	Ab3-prox1	fgf10a^tbvbo/tbvbo	standard conditions	Pec-fin	endocrine pancreas	IHC
	Ab3-prox1			Pec-fin	hepatic duct	IHC
	Ab3-prox1			Pec-fin	intestine	IHC
	Ab3-prox1			Pec-fin	liver	IHC
	Ab3-prox1			Pec-fin	pancreatic duct	IHC
	Ab3-prox1			Protruding-mouth	endocrine pancreas	IHC
	Ab3-prox1			Protruding-mouth	hepatic duct	IHC
	Ab3-prox1			Protruding-mouth	intestine	IHC
	Ab3-prox1			Protruding-mouth	liver	IHC
	Ab3-prox1			Protruding-mouth	pancreatic duct	IHC

Antibody Labeling Details

Antibody	Assay	Fish	Conditions	Stage	Anatomy
Ab-2F11	IHC	WT	standard conditions	Protruding-mouth	hepatic duct
	IHC			Protruding-mouth	pancreatic duct
	IHC	fgf10a^tbvbo/tbvbo	standard conditions	Protruding-mouth	hepatic duct
	IHC			Protruding-mouth	pancreatic duct
	IHC	fgf10a^tbvbo/tbvbo; gz15Tg	standard conditions	Day 4	hepatic duct
	IHC			Day 4	pancreatic duct
	IHC	gz15Tg	standard conditions	Day 4	hepatic duct
	IHC			Day 4	pancreatic duct

Phenotype Details

Fish	Conditions	Stage	Phenotype
fgf10a^tbvbo/tbvbo	standard conditions	Day 4	hepatocyte mislocalised, abnormal

Full text @ Nat. Genet.