Gene

prox1a

ID
ZDB-GENE-980526-397
Name
prospero homeobox 1a
Symbol
prox1a Nomenclature History
Previous Names
  • prox1 (1)
  • zgc:111888
Type
protein_coding_gene
Location
Chr: 17 Mapping Details/Browsers
Description
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including lymphangiogenesis; negative regulation of DNA-binding transcription factor activity; and neuromast development. Located in nucleus. Is expressed in several structures, including digestive system; mesoderm; nervous system; pleuroperitoneal region; and trunk vasculature. Orthologous to human PROX1 (prospero homeobox 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
170 figures from 104 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
13 figures from 7 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With prox1a Human Ortholog
No data available
Associated With prox1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR023082 Homeo-prospero domain
Family IPR039350 Prospero homeodomain family
Homologous_superfamily IPR009057 Homeobox-like domain superfamily
Homologous_superfamily IPR037131 Homeo-prospero domain superfamily
Domain Details Per Protein
Protein Length Homeobox-like domain superfamily Homeo-prospero domain Homeo-prospero domain superfamily Prospero homeodomain family
UniProtKB:Q90ZL7 739
UniProtKB:Q502S0 739
UniProtKB:Q9YHZ4 739
UniProtKB:F1QAE1 739
Transcripts
Genome Browsers
Interactions and Pathways
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab4-prox1 polyclonal IgG Goat
  • IHC
R&D Systems
6
Ab5-prox1 polyclonal IgG Rabbit
  • IHC
AngioBio
21
Ab7-prox1 polyclonal Rabbit
  • IHC
RELIA Tech
5
Ab2-Prox1 polyclonal Rabbit
  • IHC
3
Ab6-prox1 polyclonal Rabbit
  • IHC
7
Ab3-prox1 polyclonal Rabbit
  • IHC
Millipore
43
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations