ZFIN ID: ZDB-GENE-980526-397
Gene Name: prospero homeobox 1a
Gene Symbol: prox1a
Sequence Ontology ID : SO:0000704

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Previous Names: prox1 (1), zgc:111888

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(Including Attributions)
Location: Chr: 17 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 148 figures from 86 publications
Directly Submitted Expression Data: 7 figures (26 images) from Thisse et al., 2005 [eu351]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
  adaxial cell, amacrine cell, brain, caudal tuberculum (all 72) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
i278 Indel Unknown Frameshift, Premature Stop ZINC_FINGER_NUCLEASE
la027849Tg Transgenic Insertion Unknown Unknown DNA
sa23123 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa23124 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents: MO1-prox1a (1), MO2-prox1a (1), MO3-prox1a (1)
    PHENOTYPE
    Data: 12 figures from 6 publications
    Observed in: hypothalamus neuron, lymphangiogenesis, lymphatic endothelial cell differentiation, neuromast somatic stem cell (all 11) expand
    DISEASE ASSOCIATED WITH prox1a HUMAN ORTHOLOGNo data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process negative regulation of DNA binding transcription factor activity (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 13)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR007738 (1)
  • InterPro:IPR009057 (1)
  • InterPro:IPR023082 (1)
  • InterPro:IPR037131 (1)
  • PROSITE:PS51818 (1)
  • Pfam:PF05044 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA prox1a-001 (1) 3008
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIES
    Ab2-Prox1 (1), Ab3-prox1 (1), Ab4-prox1 (1), Ab5-prox1 (1), Ab6-prox1 (1) (all 6) expand
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM prox1a
    TgBAC(prox1a:Citrine), tgbac(prox1a:kalta4), TgBAC(prox1a:KALTA4,4xUAS-ADV.E1b:TagRFP)
    MARKER RELATIONSHIPS
    prox1aContained in: [BAC] DKEY-5J3 (1) (order this)
    prox1aEncodes: [EST] eu351 (1)
    [cDNA] MGC:111888 (1) (order this), MGC:191746 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131405 (1) 2839bp
    Genomic GenBank:BX928753 (1) 73008bp
    Select Tool
    Polypeptide UniProtKB:A0A0R4IFI2 (1) 739aa
    Sequence Clusters UniGene:81273 (1)
    Sequence Information (all 31)
    OTHER prox1a GENE PAGES
  • Alliance (1)
  • Gene:30679 (1)
  • VEGA:OTTDARG00000028789 (1)
  • Ensembl(GRCz10):ENSDARG00000055158 (1)
  • ORTHOLOGY for prox1a (Chr: 17)
    CITATIONS (164)