ZFIN ID: ZDB-FIG-080108-12
Potente et al., 2007 - SIRT1 controls endothelial angiogenic functions during vascular growth. Genes & Development   21(20):2644-2658 Full text @ Genes & Dev.
Anatomical Term:
Stage Range: 2-cell to Protruding-mouth
Knockdown Reagents:
Observed In:
Stage Range: Unknown to Prim-5

Fig. 4 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
sirt1 WT standard conditions 8-cell whole organism ISH
Shield whole organism ISH
14-19 somites whole organism ISH
Prim-5 whole organism ISH
Long-pec whole organism ISH
Protruding-mouth whole organism ISH
y1Tg standard conditions 2-cell to Protruding-mouth whole organism RTPCR
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
y1Tg + MO1-sirt1 standard conditions Unknown trunk vasculature spatial pattern, abnormal
y1Tg + MO2-sirt1 standard conditions Unknown blood vasculature hemorrhagic, abnormal
Unknown pericardium edematous, abnormal
Unknown trunk vasculature spatial pattern, abnormal
Prim-5 intersegmental vessel structure, abnormal
Prim-5 vasculature development disrupted, abnormal
Full text @ Genes & Dev.