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General Information
ZIRC
ZFIN ID: ZDB-ALT-180605-2
Genomic Feature: sm11
Synonyms: smu8 (1)
Affected Genomic Regions: rb1 (1)
Type: Small Deletion (1)
Protocol: embryos treated with TALEN5-rb1
Lab Of Origin: Yiyue ZHANG Lab
Location: Chr 21: 23014232 - 23014239 (GRCz11) (1) Details
Sequence:
Current Sources:
MUTATION DETAILS
DNA/cDNA Change: 8 bp deleted in Exon 2 (1)
Transcript Consequence: Frameshift (1)
Protein Consequence: Polypeptide Truncation (1)
FLANKING SEQUENCE No data available
NOTES
Comment Citation
the truncated RB1 protein lacks all functional domains. Zhang et al., 2017
OTHER sm11 PAGES No links to external sites
GENOTYPES
Zygosity Genotype (Background) Affected Genomic Regions Parental Zygosity
Homozygous rb1sm11/sm11 rb1 ♀+/- ♂+/-
Complex rb1sm11/sm11 ; zf411Tg rb1
rb1sm11/sm11 ; zf411Tg ; tp53zdf1/zdf1 rb1, tp53

CITATIONS  (1)