FIGURE SUMMARY
Title

Neuronal Expression of Fibroblast Growth Factor Receptors in Zebrafish

Authors
Rohs, P., Ebert, A.M., Zuba, A., and McFarlane, S.
Source
Full text @ Gene Expr. Patterns

In situ hybridization of fgfr1a gene expression. In situ hybridization of fgfr1a gene expression at 24 hpf (A–D), 36 hpf (E–H), 48 hpf (I–L), 60 hpf (M–P), and 72 hpf (Q–T). Lateral views (A, E, I, M, Q) with anterior to the left, dorsal at the top, dorsal views (B, F, J, N, R) with anterior to the left, rostral transverse brain sections (C, G, K, O, S), and caudal transverse brain sections (D, H, L, P, T). Dotted lines indicate approximate orientation of imaged sections. Solid arrowheads indicate the location of the midbrain–hindbrain boundary. Arrowheads in C point to weak brain expression. Labels point to expression in the ciliary marginal zone (CMZ), dorsal thalamus (DT), fin bud (FB), jaw (J), lens (L), midbrain (MB), midbrain–hindbrain boundary (MHB), midbrain tegmentum (T), neuromasts (NM), optic tectum (Te), pharyngeal arches (PA), periocular mesenchyme (POM), splanchnocranium (SC), tectal ventricle (TeVe), telencephalon (Tel), and ventral midbrain (VMB).

In situ hybridization of fgfr1b gene expression. In situ hybridization of fgfr1b gene expression at 24 hpf (A–D), 36 hpf (E–H), 48 hpf (I–L), 60 hpf (M–P), and 72 hpf (Q–T). Lateral views (A, E, I, M, Q) with anterior to the left, dorsal at the top, dorsal views (B, F, J, N, R) with anterior to the left, rostral transverse brain sections (C, G, K, O, S), and caudal transverse brain sections (D, H, L, P, T). Dotted lines indicate approximate orientation of imaged sections. Solid arrowheads indicate the location of the midbrain–hindbrain boundary. Labels point to expression in the fin bud (FB), lens (L), neuromasts (NM), optic nerve head (ONH), pharyngeal arches (PA), periocular mesenchyme (POM), tectal ventricle (TeVe), ventral diencephalon (VDi), ventral retina (VR), and ventricle (Ve). White arrowheads point to expression surrounding the lens (K, O, S).

In situ hybridization of fgfr2 gene expression. In situ hybridization of fgfr2 gene expression at 24 hpf (A–D), 36 hpf (E–H), 48 hpf (I–L), 60 hpf (M–P), and 72 hpf (Q–T). Lateral views (A, E, I, M, Q) with anterior to the left, dorsal at the top, dorsal views (B, F, J, N, R) with anterior to the left, rostral transverse brain sections (C, G, K, O, S), and caudal transverse brain sections (D, H, L, P, T). Dotted lines indicate approximate orientation of imaged sections. Solid arrowheads indicate the location of the midbrain–hindbrain boundary. Labels point to expression in the cerebellar plate (CeP), diencephalon (Di), dorsal forebrain (DFrb), dorsal midbrain (DMB), dorsal thalamus (DT), fin bud (FB), forebrain (FrB), forebrain ventricular zone (FrVe), hindbrain (HB), inner ear (E), jaw (J), lens (L), medulla oblongata (MO), midbrain (MB), otic placode (OP), periocular mesenchyme (POM), pharyngeal arches (PA), pharynx (P), rhombomere boundaries (RhB), and ventricle (Ve). In panels K and S, the asterisk draws attention to expression surrounding the lens.

In situ hybridization of fgfr3 gene expression. In situ hybridization of fgfr3 gene expression at 24 hpf (A–D), 36 hpf (E–H), 48 hpf (I–L), 60 hpf (M–P), and 72 hpf (Q–T). Lateral views (A, E, I, M, Q) with anterior to the left, dorsal at the top, dorsal views (B, F, J, N, R) with anterior to the left, rostral transverse brain sections (C, G, K, O, S), and caudal transverse brain sections (D, H, L, P, T). Dotted lines indicate approximate orientation of imaged sections. Solid arrowheads indicate the location of the midbrain–hindbrain boundary. Labels point to expression in the diencephalon (Di), hypothalamus (H), hindbrain (HB), fin bud (FB), forebrain ventricular zone (FrVe), lens (L), mandibular cartilage (MC), midbrain (MB), periocular mesenchyme (POM), rhombomere boundaries (RhB), rhombomere 1 (r1), retinal pigment epithelium (RPE), spinal cord (SC), splanchnocranium (SCr), and vagal ganglion (VG).

In situ hybridization of fgfr3 gene expression. In situ hybridization of fgfr3 gene expression at 24 hpf (A–D), 36 hpf (E–H), 48 hpf (I–L), 60 hpf (M–P), and 72 hpf (Q–T). Lateral views (A, E, I, M, Q) with anterior to the left, dorsal at the top, dorsal views (B, F, J, N, R) with anterior to the left, rostral transverse brain sections (C, G, K, O, S), and caudal transverse brain sections (D, H, L, P, T). Dotted lines indicate approximate orientation of imaged sections. Solid arrowheads indicate the location of the midbrain–hindbrain boundary. Labels point to expression in the diencephalon (Di), hypothalamus (H), hindbrain (HB), fin bud (FB), forebrain ventricular zone (FrVe), lens (L), mandibular cartilage (MC), midbrain (MB), periocular mesenchyme (POM), rhombomere boundaries (RhB), rhombomere 1 (r1), retinal pigment epithelium (RPE), spinal cord (SC), splanchnocranium (SCr), and vagal ganglion (VG).

Acknowledgments
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Reprinted from Gene expression patterns : GEP, 13(8), Rohs, P., Ebert, A.M., Zuba, A., and McFarlane, S., Neuronal Expression of Fibroblast Growth Factor Receptors in Zebrafish, 354-61, Copyright (2013) with permission from Elsevier. Full text @ Gene Expr. Patterns