Phenotypes of identified mutants. (A) A larry^hi409 mutant on day 5 shows kidney cyst (arrow) and body curvature. (B,C) Cross-section of the glomerular (arrow)-tubular (arrowhead) region of wild-type (B) and larry^hi409 (C) embryos at 50 hpf (hour post fertilization). (D) pkd2 morphant at 53 hpf shows kidney cyst (arrow) and body curvature. nc, notochord; wt, wild type; mut, mutant; control, embryo injected with standard control morpholino oligo; mph, morphant.

hi409/IFT81 is widely expressed. (A) In situ hybridization for hi409/IFT81 in an embryo at the eight-somite stage (8S), hi409/IFT81 is enriched in the notochord (arrow). (B) In embryos at 25 hpf, hi409/IFT81 is enriched in the brain ventricle (arrow). (C) In embryos at 34 hpf, hi409/IFT81 is enriched in the otic vesicle (arrow) and slightly in the pronephric duct (arrowhead).

Ciliary defects in scorpion^hi459. (A) The pronephric duct region (arrow) in a wild-type embryo at 50 hpf reacts strongly with an antibody against acetylated tubulin. (B) Confocal image shows cilia stained with this antibody in the pronephric duct of a wild-type embryo at 24 hpf. (D) Defect of the cilia in scorpion^hi459 at 50 hpf; (D) enlarged view of C. wt, wild type; 459, scorpion^hi459.

Pronephric ducts. (A,B) Cross-section through pronephric ducts (arrow on the right side; encircled on the left) in wild-type (wt) and larry^hi409 mutant (409) embryos. (C,D) Dorsal view of the pronephric ducts stained with α6F. nc, notochord.

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.