Gene
ift81
- ID
- ZDB-GENE-040714-3
- Name
- intraflagellar transport 81 homolog
- Symbol
- ift81 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to enable tubulin binding activity. Acts upstream of or within pronephros development and regulation of TOR signaling. Predicted to be located in motile cilium. Predicted to be part of intraciliary transport particle B. Predicted to be active in centrosome and cilium. Is expressed in notochord; otic vesicle; pronephric duct; and ventricular system. Human ortholog(s) of this gene implicated in short-rib thoracic dysplasia 19 with or without polydactyly. Orthologous to human IFT81 (intraflagellar transport 81).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 12 figures from 8 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| short-rib thoracic dysplasia 19 with or without polydactyly | Alliance | Short-rib thoracic dysplasia 19 with or without polydactyly | 617895 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | IFT81, calponin homology domain | IFT81, N-terminal domain superfamily | Intraflagellar transport protein 81 |
|---|---|---|---|---|
|
UniProtKB:Q6IVW2
|
675 |
Interactions and Pathways
No data available
Plasmids
No data available