Gene
ift81
- ID
- ZDB-GENE-040714-3
- Name
- intraflagellar transport 81 homolog
- Symbol
- ift81 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to have tubulin binding activity. Involved in pronephros development and regulation of TOR signaling. Predicted to localize to centrosome; cilium; and intraciliary transport particle B. Human ortholog(s) of this gene implicated in short-rib thoracic dysplasia 19 with or without polydactyly. Is expressed in notochord; otic vesicle; pronephric duct; and ventricular system. Orthologous to human IFT81 (intraflagellar transport 81).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 12 figures from 8 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| short-rib thoracic dysplasia 19 with or without polydactyly | Alliance | Short-rib thoracic dysplasia 19 with or without polydactyly | 617895 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | IFT81, calponin homology domain | IFT81, N-terminal domain superfamily | Intraflagellar transport protein 81 |
|---|---|---|---|---|
|
UniProtKB:Q6IVW2
|
675 |
Interactions and Pathways
No data available
Plasmids
No data available