ZFIN

ZFIN ID: ZDB-GENE-110519-2

ZFIN ID: ZDB-GENE-110519-2

CITATIONS (39 total)

Gene Name:	thyroid peroxidase
Gene Symbol:	tpo

Fagundes, T., Pannetier, P., Gölz, L., Behnstedt, L., Morthorst, J., Vergauwen, L., Knapen, D., Holbech, H., Braunbeck, T., Baumann, L. (2024) The generation gap in endocrine disruption: Can the integrated fish endocrine disruptor test (iFEDT) bridge the gap by assessing intergenerational effects of thyroid hormone system disruption?. Aquatic toxicology (Amsterdam, Netherlands). 272:106969106969

Fang, Y., Wan, J.P., Wang, Z., Song, S.Y., Zhang, C.X., Yang, L., Zhang, Q.Y., Yan, C.Y., Wu, F.Y., Lu, S.Y., Sun, F., Han, B., Zhao, S.X., Dong, M., Song, H.D. (2024) Deficiency of the HGF/Met pathway leads to thyroid dysgenesis by impeding late thyroid expansion. Nature communications. 15:31653165

Xu, Y., Zhang, S., Bao, Y., Luan, J., Fu, Z., Sun, M., Zhao, X., Feng, X. (2024) Melatonin protects zebrafish pancreatic development and physiological rhythms from sodium propionate-induced disturbances via the hypothalamic-pituitary-thyroid axis. Journal of the science of food and agriculture. 104(12):7454-7463

Yan, C.Y., Wu, F.Y., Sun, F., Fang, Y., Zhang, R.J., Zhang, C.R., Zhang, C.X., Wang, Z., Yang, R.M., Yang, L., Dong, M., Zhang, Q.Y., Ye, X.P., Song, H.D., Zhao, S.X. (2023) The isl2a transcription factor regulates pituitary development in zebrafish. Frontiers in endocrinology. 14:920548920548

Yang, L., Tu, P.H., Zhang, C.X., Xie, R.R., Dong, M., Jing, Y., Chen, X., Wei, G., Song, H.D. (2023) Influence of two anti-tumor drugs, pazopanib, and axitinib, on the development and thyroid-axis of zebrafish (Danio rerio) embryos/larvae. Frontiers in endocrinology. 14:12046781204678

Yang, R.M., Song, S.Y., Wu, F.Y., Yang, R.F., Shen, Y.T., Tu, P.H., Wang, Z., Zhang, J.X., Cheng, F., Gao, G.Q., Liang, J., Guo, M.M., Yang, L., Zhou, Y., Zhao, S.X., Zhan, M., Song, H.D. (2023) Myeloid cells interact with a subset of thyrocytes to promote their migration and follicle formation through NF-κB. Nature communications. 14:80828082

Ding, W., Chen, Y., Sultan, Y., Ma, J., Feng, Y., Li, X. (2022) Effect of Acute Exposure to the Ionic Liquid 1-Methyl-3-octylimidazolium Chloride on the Embryonic Development and Larval Thyroid System of Zebrafish. Animals : an open access journal from MDPI. 12(11)

Fang, Y., Wan, J.P., Zhang, R.J., Sun, F., Yang, L., Zhao, S.X., Dong, M., Song, H.D. (2022) Tpo knockout in zebrafish partially recapitulates clinical manifestations of congenital hypothyroidism and reveals the involvement of TH in proper development of glucose homeostasis. General and comparative endocrinology. 323-324:114033

Lee, J.S., Kawai, Y.K., Morita, Y., Covaci, A., Kubota, A. (2022) Estrogenic and growth inhibitory responses to organophosphorus flame retardant metabolites in zebrafish embryos. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 256:109321

Zhou, W., Wang, Y., Wang, J., Peng, C., Wang, Z., Qin, H., Li, G., Li, D. (2022) β-Ionone causes endocrine disruption, hyperpigmentation and hypoactivity in zebrafish early life stages. The Science of the total environment. 834:155433

Chu, S., Kwon, B.R., Lee, Y.M., Zoh, K.D., Choi, K. (2021) Effects of 2-ethylhexyl-4-methoxycinnamate (EHMC) on thyroid hormones and genes associated with thyroid, neurotoxic, and nephrotoxic responses in adult and larval zebrafish (Danio rerio). Chemosphere. 263:128176

Guzzolino, E., Milella, M.S., Forini, F., Borsò, M., Rutigliano, G., Gorini, F., Zucchi, R., Saba, A., Bianchi, F., Iervasi, G., Pitto, L. (2021) Thyroid disrupting effects of low-dose dibenzothiophene and cadmium in single or concurrent exposure: New evidence from a translational zebrafish model. The Science of the total environment. 769:144703

Kim, J., Lee, G., Lee, Y.M., Zoh, K.D., Choi, K. (2021) Thyroid disrupting effects of perfluoroundecanoic acid and perfluorotridecanoic acid in zebrafish (Danio rerio) and rat pituitary (GH3) cell line. Chemosphere. 262:128012

Song, J., Lu, Y., Cheng, X., Shi, C., Lou, Q., Jin, X., He, J., Zhai, G., Yin, Z. (2021) Functions of the Thyroid-Stimulating Hormone on Key Developmental Features Revealed in a Series of Zebrafish Dyshormonogenesis Models. Cells. 10(8):

Gillotay, P., Shankar, M., Haerlingen, B., Sema Elif, E., Pozo-Morales, M., Garteizgogeascoa, I., Reinhardt, S., Kränkel, A., Bläsche, J., Petzold, A., Ninov, N., Kesavan, G., Lange, C., Brand, M., Lefort, A., Libert, F., Detours, V., Costagliola, S., Singh, S.P. (2020) Single-cell transcriptome analysis reveals thyrocyte diversity in the zebrafish thyroid gland. EMBO reports. 21(12):e50612

Hutcheson, D.A., Xie, Y., Figueroa, P., Dorsky, R.I. (2020) A transgene targeted to the zebrafish nkx2.4b locus drives specific GFP expression and disrupts thyroid development. Developmental Dynamics : an official publication of the American Association of Anatomists. 249(11):1387-1393

Li, J., Dong, T., Keerthisinghe, T.P., Chen, H., Li, M., Chu, W., Yang, J., Hu, Z., Snyder, S.A., Dong, W., Fang, M. (2020) Long-term oxytetracycline exposure potentially alters brain thyroid hormone and serotonin homeostasis in zebrafish. Journal of hazardous materials. 399:123061

Reinwald, H., König, A., Ayobahan, S.U., Alvincz, J., Sipos, L., Göckener, B., Böhle, G., Shomroni, O., Hollert, H., Salinas, G., Schäfers, C., Eilebrecht, E., Eilebrecht, S. (2020) Toxicogenomic fin(ger)prints for thyroid disruption AOP refinement and biomarker identification in zebrafish embryos. The Science of the total environment. 760:143914

Giusti, N., Gillotay, P., Trubiroha, A., Opitz, R., Dumont, J.E., Costagliola, S., De Deken, X. (2019) Inhibition of the thyroid hormonogenic H₂O₂ production by Duox/DuoxA in zebrafish reveals VAS2870 as a new goitrogenic compound. Molecular and Cellular Endocrinology. 500:110635

Jarque, S., Ibarra, J., Rubio-Brotons, M., García-Fernández, J., Terriente, J. (2019) Multiplex Analysis Platform for Endocrine Disruption Prediction Using Zebrafish. International Journal of Molecular Sciences. 20(7):

Shi, G., Wang, J., Guo, H., Sheng, N., Cui, Q., Pan, Y., Guo, Y., Sun, Y., Dai, J. (2019) Parental exposure to 6:2 chlorinated polyfluorinated ether sulfonate (F-53B) induced transgenerational thyroid hormone disruption in zebrafish. The Science of the total environment. 665:855-863

Sarasquete, C., Úbeda-Manzanaro, M., Ortiz-Delgado, J.B. (2018) Toxicity and non-harmful effects of the soya isoflavones, genistein and daidzein, in embryos of the zebrafish, Danio rerio. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 211:57-67

Vergauwen, L., Cavallin, J.E., Ankley, G.T., Bars, C., Gabriëls, I.J., Michiels, E.D.G., Fitzpatrick, K.R., Periz-Stanacev, J., Randolph, E.C., Robinson, S.L., Saari, T.W., Schroeder, A.L., Stinckens, E., Swintek, J., Van Cruchten, S.J., Verbueken, E., Villeneuve, D.L., Knapen, D. (2018) Gene transcription ontogeny of hypothalamic-pituitary-thyroid axis development in early-life stage fathead minnow and zebrafish. General and comparative endocrinology. 266:87-100

Dong, X., Xu, H., Wu, X., Yang, L. (2017) Multiple bioanalytical method to reveal developmental biological responses in zebrafish embryos exposed to triclocarban. Chemosphere. 193:251-258

Jinchao, Y., Yanling, Z., Xu, W., Bing, Z., Yuhao, Y., Weiran, Z., Shaoyang, S., Liyun, M., Yun, S., Ling, Z., Min, Y., Wei, M. (2017) Thrombopoietic stimulating activity of rhTyrRS (Y341A). Scientific Reports. 7:12184

Baumann, L., Ros, A., Rehberger, K., Neuhauss, S.C., Segner, H. (2016) Thyroid disruption in zebrafish (Danio rerio) larvae: Different molecular response patterns lead to impaired eye development and visual functions. Aquatic toxicology (Amsterdam, Netherlands). 172:44-55

Fetter, E., Baldauf, L., Da Fonte, D.F., Ortmann, J., Scholz, S. (2015) Comparative analysis of goitrogenic effects of phenylthiourea and methimazole in zebrafish embryos. Reproductive toxicology (Elmsford, N.Y.). 57:10-20

Pappalardo, A., Porreca, I., Caputi, L., De Felice, E., Schulte-Merker, S., Zannini, M., Sordino, P. (2015) Thyroid development in zebrafish lacking Taz. Mechanisms of Development. 138 Pt 3:268-78

Liu, Y., Wang, J., Fang, X., Zhang, H., and Dai, J. (2011) The thyroid-disrupting effects of long-term perfluorononanoate exposure on zebrafish (Danio rerio). Ecotoxicology (London, England). 20(1):47-55

Opitz, R., Maquet, E., Zoenen, M., Dadhich, R., and Costagliola, S. (2011) TSH Receptor Function Is Required for Normal Thyroid Differentiation in Zebrafish. Molecular endocrinology (Baltimore, Md.). 25(9):1579-99

Shi, X., Liu, C., Wu, G., and Zhou, B. (2009) Waterborne exposure to PFOS causes disruption of the hypothalamus-pituitary-thyroid axis in zebrafish larvae. Chemosphere. 77(7):1010-1018

Additional Citations (8):

ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.

ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.

Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.

ZFIN Staff (2003) Curation of orthology data. Manually curated data.

ZFIN Staff (2003) Curation of unpublished nucleotide sequence accession numbers. Manually curated data.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of UniProt Keywords with GO Terms. Automated Data Submission.

ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission.