Research
Search
Genes / Clones
Expression
Mutants / Tg
Antibodies
Anatomy / GO / Human Disease / Chemical
Publications
Data Mining
Downloads
Data Model
AllianceMine
BioMart
Genomics
BLAST
ZFIN
Ensembl
NCBI
UCSC
Genome Browsers
ZFIN
Ensembl
Vega
GRC
UCSC
NCBI
Resources
Zebrafish Genomics
Other Genome Databases
Resources
General
The Zebrafish Book
Protocol Wiki
Antibody Wiki
Anatomy Atlases
Resources for Students and Educators
Zebrafish Programs
ZF-Health
Husbandry Resources
More...
Resource Centers
Zebrafish International Resource Center (ZIRC)
China Zebrafish Resource Center (CZRC)
European Zebrafish Resource Center (EZRC)
Community
Announcements
News
Meetings
Jobs
Alliance Community Forum
Search
People
Labs
Companies
Societies
International Zebrafish Society (IZFS)
Zebrafish Disease Models Society (ZDMS)
Genetics Society of America (GSA)
Zebrafish Husbandry Association
Support
Nomenclature
Nomenclature Conventions
Line Designations
Wild-Type Lines
Submit a Proposed Gene Name
Submit a Proposed Mutant/Tg Line Name
Publications
Guidelines for Authors
Zebrashare
Citing ZFIN
Using ZFIN
Help & Tips
Glossary
Single Box Search Help
Submit Data
Terms of Use
About Us
About ZFIN
Contact Information
Statistics
Committees
Jobs at ZFIN
Sign In
ZFIN ID:
ZDB-GENE-070206-1
CITATIONS
(36 total)
Gene Name:
neurexin 1a
Gene Symbol:
nrxn1a
Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613
Caioni, G., Merola, C., Perugini, M., d'Angelo, M., Cimini, A.M., Amorena, M., Benedetti, E. (2021) An Experimental Approach to Study the Effects of Realistic Environmental Mixture of Linuron and Propamocarb on Zebrafish Synaptogenesis. International Journal of Environmental Research and Public Health. 18(9):
Dwivedi, S., Medishetti, R., Rani, R., Sevilimedu, A., Kulkarni, P., Yogeeswari, P. (2019) Larval zebrafish model for studying the effects of valproic acid on neurodevelopment: An approach towards modeling autism. Journal of Pharmacological and Toxicological Methods. 95:56-65
Ehrmann, I., Dalgliesh, C., Liu, Y., Danilenko, M., Crosier, M., Overman, L., Arthur, H.M., Lindsay, S., Clowry, G.J., Venables, J.P., Fort, P., and Elliott, D.J. (2013) The tissue-specific RNA binding protein T-STAR controls regional splicing patterns of neurexin pre-mRNAs in the brain. PLoS Genetics. 9(4):e1003474
Gabellini, C., Pucci, C., De Cesari, C., Martini, D., Di Lauro, C., Digregorio, M., Norton, W., Zippo, A., Sessa, A., Broccoli, V., Andreazzoli, M. (2022) CRISPR/Cas9-Induced Inactivation of the Autism-Risk Gene
setd5
Leads to Social Impairments in Zebrafish. International Journal of Molecular Sciences. 24(1):
Koh, A., Tao, S., Jing, G.Y., Chaganty, V., See, K., Purushothaman, K., Orbán, L., Mathuru, A.S., Wohland, T., Winkler, C. (2020) A Neurexin2aa deficiency results in axon pathfinding defects and increased anxiety in zebrafish. Human molecular genetics. 29(23):3765-3780
Maugars, G., Dufour, S. (2015) Demonstration of the Coexistence of Duplicated LH Receptors in Teleosts, and Their Origin in Ancestral Actinopterygians. PLoS One. 10:e0135184
Milash, B., Gao, J., Stevenson, T.J., Son, J.H., Dahl, T., Bonkowsky, J.L. (2016) Temporal Dysynchrony in brain connectivity gene expression following hypoxia. BMC Genomics. 17:334
Mo, W., and Nicolson, T. (2011) Both pre- and postsynaptic activity of nsf prevents degeneration of hair-cell synapses. PLoS One. 6(11):e27146
Moravec, C.E., Samuel, J., Weng, W., Wood, I.C., Sirotkin, H.I. (2016) Maternal Rest/Nrsf Regulates Zebrafish Behavior through snap25a/b. The Journal of neuroscience : the official journal of the Society for Neuroscience. 36:9407-19
Rissone, A., Foglia, E., Sangiorgio, L., Cermenati, S., Nicoli, S., Cimbro, S., Beltrame, M., Bussolino, F., Cotelli, F., and Arese, M. (2012) The Synaptic Proteins beta-Neurexin and Neuroligin Synergize With Extracellular Matrix-Binding Vascular Endothelial Growth Factor A During Zebrafish Vascular Development. Arterioscler. Thromb. Vasc. Biol.. 32(7):1563-1572
Rissone, A., Monopoli, M., Beltrame, M., Bussolino, F., Cotelli, F., and Arese, M. (2007) Comparative Genome Analysis of the Neurexin Gene Family in Danio rerio: Insights into Their Functions and Evolution. Mol. Biol. Evol.. 24(1):236-252
Shah, A.N., Davey, C.F., Whitebirch, A.C., Miller, A.C., Moens, C.B. (2015) Rapid reverse genetic screening using CRISPR in zebrafish. Nature Methods. 12(6):535-40
Tromp, A., Robinson, K., Hall, T.E., Mowry, B., Giacomotto, J. (2021) Pipeline for generating stable large genomic deletions in zebrafish, from small domains to whole gene excisions. G3 (Bethesda). 11(12):
Tu, H., Peng, T., Liu, J., Chen, X., Fan, C., Huang, Z., Zhang, Y., Zou, F., Meng, X. (2017) Role of neurexin2a in lead-induced locomotor defect in developing zebrafish. Aquatic toxicology (Amsterdam, Netherlands). 194:167-175
Varshney, G.K., Lu, J., Gildea, D., Huang, H., Pei, W., Yang, Z., Huang, S.C., Schoenfeld, D.S., Pho, N., Casero, D., Hirase, T., Mosbrook-Davis, D.M., Zhang, S., Jao, L.E., Zhang, B., Woods, I.G., Zimmerman, S., Schier, A.F., Wolfsberg, T., Pellegrini, M., Burgess, S.M., and Lin, S. (2013) A large-scale zebrafish gene knockout resource for the genome-wide study of gene function. Genome research. 23(4):727-735
Wang, D., Jao, L.E., Zheng, N., Dolan, K., Ivey, J., Zonies, S., Wu, X., Wu, K., Yang, H., Meng, Q., Zhu, Z., Zhang, B., Lin, S., and Burgess, S.M. (2007) Efficient genome-wide mutagenesis of zebrafish genes by retroviral insertions. Proceedings of the National Academy of Sciences of the United States of America. 104(30):12428-12433
Wang, Y., Shen, C., Wang, C., Zhou, Y., Gao, D., Zuo, Z. (2017) Maternal and embryonic exposure to the water soluble fraction of crude oil or lead induces behavioral abnormalities in zebrafish (Danio rerio), and the mechanisms involved. Chemosphere. 191:7-16
Wang, Y., Zhong, H., Wang, C., Gao, D., Zhou, Y., Zuo, Z. (2016) Maternal exposure to the water soluble fraction of crude oil, lead and their mixture induces autism-like behavioral deficits in zebrafish (Danio rerio) larvae. Ecotoxicology and environmental safety. 134P1:23-30
Gabellini, C., Pucci, C., De Cesari, C., Martini, D., Di Lauro, C., Digregorio, M., Norton, W., Zippo, A., Sessa, A., Broccoli, V., Andreazzoli, M. (2022) CRISPR/Cas9-Induced Inactivation of the Autism-Risk Gene
setd5
Leads to Social Impairments in Zebrafish. International Journal of Molecular Sciences. 24(1):
Caioni, G., Merola, C., Perugini, M., d'Angelo, M., Cimini, A.M., Amorena, M., Benedetti, E. (2021) An Experimental Approach to Study the Effects of Realistic Environmental Mixture of Linuron and Propamocarb on Zebrafish Synaptogenesis. International Journal of Environmental Research and Public Health. 18(9):
Tromp, A., Robinson, K., Hall, T.E., Mowry, B., Giacomotto, J. (2021) Pipeline for generating stable large genomic deletions in zebrafish, from small domains to whole gene excisions. G3 (Bethesda). 11(12):
Koh, A., Tao, S., Jing, G.Y., Chaganty, V., See, K., Purushothaman, K., Orbán, L., Mathuru, A.S., Wohland, T., Winkler, C. (2020) A Neurexin2aa deficiency results in axon pathfinding defects and increased anxiety in zebrafish. Human molecular genetics. 29(23):3765-3780
Dwivedi, S., Medishetti, R., Rani, R., Sevilimedu, A., Kulkarni, P., Yogeeswari, P. (2019) Larval zebrafish model for studying the effects of valproic acid on neurodevelopment: An approach towards modeling autism. Journal of Pharmacological and Toxicological Methods. 95:56-65
Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613
Tu, H., Peng, T., Liu, J., Chen, X., Fan, C., Huang, Z., Zhang, Y., Zou, F., Meng, X. (2017) Role of neurexin2a in lead-induced locomotor defect in developing zebrafish. Aquatic toxicology (Amsterdam, Netherlands). 194:167-175
Wang, Y., Shen, C., Wang, C., Zhou, Y., Gao, D., Zuo, Z. (2017) Maternal and embryonic exposure to the water soluble fraction of crude oil or lead induces behavioral abnormalities in zebrafish (Danio rerio), and the mechanisms involved. Chemosphere. 191:7-16
Milash, B., Gao, J., Stevenson, T.J., Son, J.H., Dahl, T., Bonkowsky, J.L. (2016) Temporal Dysynchrony in brain connectivity gene expression following hypoxia. BMC Genomics. 17:334
Moravec, C.E., Samuel, J., Weng, W., Wood, I.C., Sirotkin, H.I. (2016) Maternal Rest/Nrsf Regulates Zebrafish Behavior through snap25a/b. The Journal of neuroscience : the official journal of the Society for Neuroscience. 36:9407-19
Wang, Y., Zhong, H., Wang, C., Gao, D., Zhou, Y., Zuo, Z. (2016) Maternal exposure to the water soluble fraction of crude oil, lead and their mixture induces autism-like behavioral deficits in zebrafish (Danio rerio) larvae. Ecotoxicology and environmental safety. 134P1:23-30
Maugars, G., Dufour, S. (2015) Demonstration of the Coexistence of Duplicated LH Receptors in Teleosts, and Their Origin in Ancestral Actinopterygians. PLoS One. 10:e0135184
Shah, A.N., Davey, C.F., Whitebirch, A.C., Miller, A.C., Moens, C.B. (2015) Rapid reverse genetic screening using CRISPR in zebrafish. Nature Methods. 12(6):535-40
Ehrmann, I., Dalgliesh, C., Liu, Y., Danilenko, M., Crosier, M., Overman, L., Arthur, H.M., Lindsay, S., Clowry, G.J., Venables, J.P., Fort, P., and Elliott, D.J. (2013) The tissue-specific RNA binding protein T-STAR controls regional splicing patterns of neurexin pre-mRNAs in the brain. PLoS Genetics. 9(4):e1003474
Varshney, G.K., Lu, J., Gildea, D., Huang, H., Pei, W., Yang, Z., Huang, S.C., Schoenfeld, D.S., Pho, N., Casero, D., Hirase, T., Mosbrook-Davis, D.M., Zhang, S., Jao, L.E., Zhang, B., Woods, I.G., Zimmerman, S., Schier, A.F., Wolfsberg, T., Pellegrini, M., Burgess, S.M., and Lin, S. (2013) A large-scale zebrafish gene knockout resource for the genome-wide study of gene function. Genome research. 23(4):727-735
Rissone, A., Foglia, E., Sangiorgio, L., Cermenati, S., Nicoli, S., Cimbro, S., Beltrame, M., Bussolino, F., Cotelli, F., and Arese, M. (2012) The Synaptic Proteins beta-Neurexin and Neuroligin Synergize With Extracellular Matrix-Binding Vascular Endothelial Growth Factor A During Zebrafish Vascular Development. Arterioscler. Thromb. Vasc. Biol.. 32(7):1563-1572
Mo, W., and Nicolson, T. (2011) Both pre- and postsynaptic activity of nsf prevents degeneration of hair-cell synapses. PLoS One. 6(11):e27146
Rissone, A., Monopoli, M., Beltrame, M., Bussolino, F., Cotelli, F., and Arese, M. (2007) Comparative Genome Analysis of the Neurexin Gene Family in Danio rerio: Insights into Their Functions and Evolution. Mol. Biol. Evol.. 24(1):236-252
Wang, D., Jao, L.E., Zheng, N., Dolan, K., Ivey, J., Zonies, S., Wu, X., Wu, K., Yang, H., Meng, Q., Zhu, Z., Zhang, B., Lin, S., and Burgess, S.M. (2007) Efficient genome-wide mutagenesis of zebrafish genes by retroviral insertions. Proceedings of the National Academy of Sciences of the United States of America. 104(30):12428-12433
Additional Citations (17):
Burgess, S., and Lin, S. (2012) Viral Insertion Mutants Overwrite Data. ZFIN Direct Data Submission.
Burgess, S., and Lin, S. (2011) Viral Insertion Mutants. ZFIN Direct Data Submission.
Busch-Nentwich, E., Kettleborough, R., Dooley, C. M., Scahill, C., Sealy, I., White, R., Herd, C., Mehroke, S., Wali, N., Carruthers, S., Hall, A., Collins, J., Gibbons, R., Pusztai, Z., Clark, R., and Stemple, D.L. (2013) Sanger Institute Zebrafish Mutation Project mutant data submission. ZFIN Direct Data Submission.
GOA curators, UniProt curators (2007) Gene Ontology annotation based on Swiss-Prot Subcellular Location vocabulary mapping. Manually curated data.
UniProt-GOA (2011) Gene Ontology annotation based on the automatic assignment of UniProtKB Subcellular Location terms in UniProtKB/TrEMBL entries. Manually curated data.
Varshney, G.K., Zhang, S., Burgess, S.M., ZFIN Staff (2015) Automated Data Load From CRISPRz. ZFIN Direct Data Submission.
Zebrafish Nomenclature Committee (2022) Nomenclature Data Curation (2022). Nomenclature Committee Submission.
ZFIN Staff (2022) Electronic Gene Ontology annotations created by ARBA machine learning models. Automated Data Submission.
ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.
ZFIN Staff (2006) Curation of Ensembl Database Links. Automated Data Submission.
ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.
ZFIN Staff (2002) Gene Ontology Annotation Through Association of UniProt Keywords with GO Terms. Automated Data Submission.
ZFIN Staff (2007) Microarray Expression to Gene Association in ZFIN. Semi-automated Curation.
ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.
ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.
ZFIN Staff (2020) Addition of links from ZFIN to Expression Atlas. Semi-automated Curation.
ZFIN Staff (2003) Curation of VEGA Database Links. Automated Data Submission.
ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.
Zebrafish Nomenclature Committee (2022) Nomenclature Data Curation (2022). Nomenclature Committee Submission.
ZFIN Staff (2022) Electronic Gene Ontology annotations created by ARBA machine learning models. Automated Data Submission.
ZFIN Staff (2020) Addition of links from ZFIN to Expression Atlas. Semi-automated Curation.
ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.
Varshney, G.K., Zhang, S., Burgess, S.M., ZFIN Staff (2015) Automated Data Load From CRISPRz. ZFIN Direct Data Submission.
Busch-Nentwich, E., Kettleborough, R., Dooley, C. M., Scahill, C., Sealy, I., White, R., Herd, C., Mehroke, S., Wali, N., Carruthers, S., Hall, A., Collins, J., Gibbons, R., Pusztai, Z., Clark, R., and Stemple, D.L. (2013) Sanger Institute Zebrafish Mutation Project mutant data submission. ZFIN Direct Data Submission.
ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.
Burgess, S., and Lin, S. (2012) Viral Insertion Mutants Overwrite Data. ZFIN Direct Data Submission.
Burgess, S., and Lin, S. (2011) Viral Insertion Mutants. ZFIN Direct Data Submission.
UniProt-GOA (2011) Gene Ontology annotation based on the automatic assignment of UniProtKB Subcellular Location terms in UniProtKB/TrEMBL entries. Manually curated data.
GOA curators, UniProt curators (2007) Gene Ontology annotation based on Swiss-Prot Subcellular Location vocabulary mapping. Manually curated data.
ZFIN Staff (2007) Microarray Expression to Gene Association in ZFIN. Semi-automated Curation.
ZFIN Staff (2006) Curation of Ensembl Database Links. Automated Data Submission.
ZFIN Staff (2003) Curation of VEGA Database Links. Automated Data Submission.
ZFIN Staff (2002) Gene Ontology Annotation Through Association of UniProt Keywords with GO Terms. Automated Data Submission.
ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.
Your Input Welcome
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.
Please check the highlighted fields and try again.
Name:
Institution:
Email address:
Please leave blank:
Subject:
Comments:
Send your comments
Thank you for submitting comments. Your input has been emailed to ZFIN curators who may contact you if additional information is required.
Oops. Something went wrong. Please try again later.