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General Information
ZIRC
ZFIN ID: ZDB-GENE-070206-1
Gene Name: neurexin 1a
Gene Symbol: nrxn1a
Sequence Ontology ID : SO:0001217

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Previous Names: nrxn1aa, nrxn1ab

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(Including Attributions)
Location: Chr: 12 Mapping Details/Browsers
Nomenclature History
Note: nrxn1a has two isoforms, alpha (DQ641424) and beta (DQ641425)
AUTOMATED DESCRIPTION
Predicted to have metal ion binding activity. Involved in sprouting angiogenesis. Predicted to localize to the integral component of membrane. Human ortholog(s) of this gene implicated in  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la018138Tg Transgenic Insertion Unknown Unknown DNA
sa641 Point Mutation Unknown Premature Stop ENU
sa4466 Point Mutation Unknown Splice Site ENU
sa15915 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa35299 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    DISEASE ASSOCIATED WITH nrxn1a HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Pitt-Hopkins-like syndrome 2 Pitt-Hopkins-like syndrome 2 614325
    {Schizophrenia, susceptibility to, 17} 614332
    DISEASE ASSOCIATED WITH nrxn1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process sprouting angiogenesis (more)
    Cellular Component integral component of membrane (more)
    Molecular Function metal ion binding (more)
    GO Terms (all 5)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    ncRNA nrxn1a-004 (1) 906
    mRNA nrxn1a-201 (1) 1425
    nrxn1a-202 (1) 3069
    nrxn1a-204 (1) 7007
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM nrxn1a No data available
    MARKER RELATIONSHIPS
    nrxn1a Contained in: [BAC] CH211-10G22 (1) (order this), DKEY-4P13 (1) (order this), DKEY-186O1 (1) (order this), DKEY-220B14 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001080021 (1) 6406 bp
    Genomic RefSeq:NW_018394843 (1) Blast at MegaBLAST
    Polypeptide UniProtKB:A1XQX0 (1) 1491 aa
    Sequence Clusters UniGene:19533 (1)
    Sequence Information (all 92)
    ORTHOLOGY for nrxn1a ( Chr: 12 )
    CITATIONS (28)