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ZFIN ID:
ZDB-GENE-060526-132
CITATIONS
(44 total)
Gene Name:
acetyl-CoA carboxylase beta
Gene Symbol:
acacb
Chen, S., Ye, W., Clements, K.D., Zan, Z., Zhao, W., Zou, H., Wang, G., Wu, S. (2022)
Bacillus licheniformis
FA6 Affects Zebrafish Lipid Metabolism through Promoting Acetyl-CoA Synthesis and Inhibiting β-Oxidation. International Journal of Molecular Sciences. 24(1):
Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
Fei, F., Sun, S.Y., Yao, Y.X., Wang, X. (2017) [Generation and phenotype analysis of zebrafish mutations of obesity-related genes lepr and mc4r]. Sheng li xue bao : [Acta physiologica Sinica]. 69:61-69
Fong, H.C., Ho, J.C., Cheung, A.H., Lai, K.P., Tse, W.K. (2016) Developmental toxicity of the common UV filter, benophenone-2, in zebrafish embryos. Chemosphere. 164:413-420
Hasumura, T., Shimada, Y., Kuroyanagi, J., Nishimura, Y., Meguro, S., Takema, Y., and Tanaka, T. (2012) Green tea extract suppresses adiposity and affects the expression of lipid metabolism genes in diet-induced obese zebrafish. Nutrition & metabolism. 9(1):73
Ho, J.C., Hsiao, C.D., Kawakami, K., Tse, W.K. (2016) Triclosan (TCS) exposure impairs lipid metabolism in zebrafish embryos. Aquatic toxicology (Amsterdam, Netherlands). 173:29-35
Jeon, H.J., Lee, Y.H., Kim, M.J., Choi, S.D., Park, B.J., Lee, S.E. (2016) Integrated biomarkers induced by chlorpyrifos in two different life stages of zebrafish (Danio rerio) for environmental risk assessment. Environmental Toxicology and Pharmacology. 43:166-174
Kim, K., Jeon, H.J., Choi, S.D., Tsang, D.C.W., Oleszczuk, P., Ok, Y.S., Lee, H.S., Lee, S.E. (2017) Combined toxicity of endosulfan and phenanthrene mixtures and induced molecular changes in adult Zebrafish (Danio rerio). Chemosphere. 194:30-41
Kim, Y.C., Lee, S.R., Jeon, H.J., Kim, K., Kim, M.J., Choi, S.D., Lee, S.E. (2020) Acute toxicities of fluorene, fluorene-1-carboxylic acid, and fluorene-9-carboxylic acid on zebrafish embryos (Danio rerio): Molecular mechanisms of developmental toxicities of fluorene-1-carboxylic acid. Chemosphere. 260:127622
Lin, J.N., Chang, L.L., Lai, C.H., Lin, K.J., Lin, M.F., Yang, C.H., Lin, H.H., Chen, Y.H. (2015) Development of an Animal Model for Alcoholic Liver Disease in Zebrafish. Zebrafish. 12(4):271-80
Liu, N., Zhang, S., Liu, Y., Lu, X., He, X. (2025) Potential Mechanisms Underlying Carbimazole-Induced Cardiotoxicity and Hepatotoxicity in Zebrafish. Journal of applied toxicology : JAT. :
Lu, J.W., Yang, W.Y., Lin, Y.M., Jin, S.L., and Yuh, C.H. (2013) Hepatitis B virus X antigen and aflatoxin B1 synergistically cause hepatitis, steatosis and liver hyperplasia in transgenic zebrafish. Acta histochemica. 115(7):728-39
Pai, W.Y., Hsu, C.C., Lai, C.Y., Chang, T.Z., Tsai, Y.L., and Her, G.M. (2013) Cannabinoid receptor 1 promotes hepatic lipid accumulation and lipotoxicity through the induction of SREBP-1c expression in zebrafish. Transgenic Research. 22(4):823-38
Seiliez, I., Médale, F., Aguirre, P., Larquier, M., Lanneretonne, L., Alami-Durante, H., Panserat, S., and Skiba-Cassy, S. (2013) Postprandial regulation of growth- and metabolism-related factors in zebrafish. Zebrafish. 10(2):237-248
Shieh, Y.S., Chang, Y.S., Hong, J.R., Chen, L.J., Jou, L.K., Hsu, C.C., and Her, G.M. (2010) Increase of hepatic fat accumulation by liver specific expression of Hepatitis B virus X protein in zebrafish. Biochimica et biophysica acta. Molecular and cell biology of lipids. 1801(7):721-730
Vohra, M.S., Ahmad, B., Taylor, E.R., Benchoula, K., Fong, I.L., Parhar, I.S., Ogawa, S., Serpell, C.J., Wong, E.H. (2025) 5,7,3',4',5'-Pentamethoxyflavone (PMF) Exhibits Anti-Obesity and Neuroprotective Effects in an Obese Zebrafish Model. Molecular and Cellular Endocrinology. :112554112554
Wan, G., and Chan, K.M. (2010) A study of somatolactin actions by ectopic expression in transgenic zebrafish larvae. Journal of molecular endocrinology. 45(5):301-315
Wang, Y., Bo, J., Zhao, Z., Han, Y., Zhang, Q., Liu, L. (2023) Depletion of Igfbp7 alleviates zebrafish NAFLD progression through inhibiting hepatic ferroptosis. Life sciences. 332:122086
Yi, S., Chen, P., Yang, L., Zhu, L. (2019) Probing the hepatotoxicity mechanisms of novel chlorinated polyfluoroalkyl sulfonates to zebrafish larvae: Implication of structural specificity. Environment International. 133:105262
Zheng, J.L., Luo, Z., Zhu, Q.L., Tan, X.Y., Chen, Q.L., Sun, L.D., and Hu, W. (2013) Molecular cloning and expression pattern of 11 genes involved in lipid metabolism in yellow catfish Pelteobagrus fulvidraco. Gene. 531(1):53-63
Liu, N., Zhang, S., Liu, Y., Lu, X., He, X. (2025) Potential Mechanisms Underlying Carbimazole-Induced Cardiotoxicity and Hepatotoxicity in Zebrafish. Journal of applied toxicology : JAT. :
Vohra, M.S., Ahmad, B., Taylor, E.R., Benchoula, K., Fong, I.L., Parhar, I.S., Ogawa, S., Serpell, C.J., Wong, E.H. (2025) 5,7,3',4',5'-Pentamethoxyflavone (PMF) Exhibits Anti-Obesity and Neuroprotective Effects in an Obese Zebrafish Model. Molecular and Cellular Endocrinology. :112554112554
Wang, Y., Bo, J., Zhao, Z., Han, Y., Zhang, Q., Liu, L. (2023) Depletion of Igfbp7 alleviates zebrafish NAFLD progression through inhibiting hepatic ferroptosis. Life sciences. 332:122086
Chen, S., Ye, W., Clements, K.D., Zan, Z., Zhao, W., Zou, H., Wang, G., Wu, S. (2022)
Bacillus licheniformis
FA6 Affects Zebrafish Lipid Metabolism through Promoting Acetyl-CoA Synthesis and Inhibiting β-Oxidation. International Journal of Molecular Sciences. 24(1):
Kim, Y.C., Lee, S.R., Jeon, H.J., Kim, K., Kim, M.J., Choi, S.D., Lee, S.E. (2020) Acute toxicities of fluorene, fluorene-1-carboxylic acid, and fluorene-9-carboxylic acid on zebrafish embryos (Danio rerio): Molecular mechanisms of developmental toxicities of fluorene-1-carboxylic acid. Chemosphere. 260:127622
Yi, S., Chen, P., Yang, L., Zhu, L. (2019) Probing the hepatotoxicity mechanisms of novel chlorinated polyfluoroalkyl sulfonates to zebrafish larvae: Implication of structural specificity. Environment International. 133:105262
Fei, F., Sun, S.Y., Yao, Y.X., Wang, X. (2017) [Generation and phenotype analysis of zebrafish mutations of obesity-related genes lepr and mc4r]. Sheng li xue bao : [Acta physiologica Sinica]. 69:61-69
Kim, K., Jeon, H.J., Choi, S.D., Tsang, D.C.W., Oleszczuk, P., Ok, Y.S., Lee, H.S., Lee, S.E. (2017) Combined toxicity of endosulfan and phenanthrene mixtures and induced molecular changes in adult Zebrafish (Danio rerio). Chemosphere. 194:30-41
Fong, H.C., Ho, J.C., Cheung, A.H., Lai, K.P., Tse, W.K. (2016) Developmental toxicity of the common UV filter, benophenone-2, in zebrafish embryos. Chemosphere. 164:413-420
Ho, J.C., Hsiao, C.D., Kawakami, K., Tse, W.K. (2016) Triclosan (TCS) exposure impairs lipid metabolism in zebrafish embryos. Aquatic toxicology (Amsterdam, Netherlands). 173:29-35
Jeon, H.J., Lee, Y.H., Kim, M.J., Choi, S.D., Park, B.J., Lee, S.E. (2016) Integrated biomarkers induced by chlorpyrifos in two different life stages of zebrafish (Danio rerio) for environmental risk assessment. Environmental Toxicology and Pharmacology. 43:166-174
Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
Lin, J.N., Chang, L.L., Lai, C.H., Lin, K.J., Lin, M.F., Yang, C.H., Lin, H.H., Chen, Y.H. (2015) Development of an Animal Model for Alcoholic Liver Disease in Zebrafish. Zebrafish. 12(4):271-80
Lu, J.W., Yang, W.Y., Lin, Y.M., Jin, S.L., and Yuh, C.H. (2013) Hepatitis B virus X antigen and aflatoxin B1 synergistically cause hepatitis, steatosis and liver hyperplasia in transgenic zebrafish. Acta histochemica. 115(7):728-39
Pai, W.Y., Hsu, C.C., Lai, C.Y., Chang, T.Z., Tsai, Y.L., and Her, G.M. (2013) Cannabinoid receptor 1 promotes hepatic lipid accumulation and lipotoxicity through the induction of SREBP-1c expression in zebrafish. Transgenic Research. 22(4):823-38
Seiliez, I., Médale, F., Aguirre, P., Larquier, M., Lanneretonne, L., Alami-Durante, H., Panserat, S., and Skiba-Cassy, S. (2013) Postprandial regulation of growth- and metabolism-related factors in zebrafish. Zebrafish. 10(2):237-248
Zheng, J.L., Luo, Z., Zhu, Q.L., Tan, X.Y., Chen, Q.L., Sun, L.D., and Hu, W. (2013) Molecular cloning and expression pattern of 11 genes involved in lipid metabolism in yellow catfish Pelteobagrus fulvidraco. Gene. 531(1):53-63
Hasumura, T., Shimada, Y., Kuroyanagi, J., Nishimura, Y., Meguro, S., Takema, Y., and Tanaka, T. (2012) Green tea extract suppresses adiposity and affects the expression of lipid metabolism genes in diet-induced obese zebrafish. Nutrition & metabolism. 9(1):73
Shieh, Y.S., Chang, Y.S., Hong, J.R., Chen, L.J., Jou, L.K., Hsu, C.C., and Her, G.M. (2010) Increase of hepatic fat accumulation by liver specific expression of Hepatitis B virus X protein in zebrafish. Biochimica et biophysica acta. Molecular and cell biology of lipids. 1801(7):721-730
Wan, G., and Chan, K.M. (2010) A study of somatolactin actions by ectopic expression in transgenic zebrafish larvae. Journal of molecular endocrinology. 45(5):301-315
Additional Citations (24):
Busch-Nentwich, E., Kettleborough, R., Dooley, C. M., Scahill, C., Sealy, I., White, R., Herd, C., Mehroke, S., Wali, N., Carruthers, S., Hall, A., Collins, J., Gibbons, R., Pusztai, Z., Clark, R., and Stemple, D.L. (2013) Sanger Institute Zebrafish Mutation Project mutant data submission. ZFIN Direct Data Submission.
Busch-Nentwich, E., Kettleborough, R., Harvey, S., Collins, J., Ding, M., Dooley, C., Fenyes, F., Gibbons, R., Herd, C., Mehroke, S., Scahill, C., Sealy, I., Wali, N., White, R., and Stemple, D.L. (2012) Sanger Institute Zebrafish Mutation Project mutant, phenotype and image data submission. ZFIN Direct Data Submission.
Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.
UniProt curators (2015) Electronic Gene Ontology annotations created by transferring manual GO annotations between related proteins based on shared sequence features.. Automated Data Submission.
UniProt-GOA (2012) Gene Ontology annotation based on UniPathway vocabulary mapping. Manually curated data.
ZFIN Staff (2002) Curation of EMBL records. Automated Data Submission.
ZFIN Staff (2024) Association of Ensembl transcripts with ZFIN genes. Semi-automated Curation.
ZFIN Staff (2022) Electronic Gene Ontology annotations created by ARBA machine learning models. Automated Data Submission.
ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.
ZFIN Staff (2006) Curation of Ensembl Database Links. Automated Data Submission.
ZFIN Staff (2002) Scientific Curation. Manually curated data.
ZFIN Staff (2003) Curation of orthology data. Manually curated data.
ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.
ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission.
ZFIN Staff (2002) Gene Ontology Annotation Through Association of UniProt Keywords with GO Terms. Automated Data Submission.
ZFIN Staff (2003) Gene Ontology Annotation Through Association of Enzyme Commission numbers with GO Terms. Automated Data Submission.
ZFIN Staff (2015) Data Model Change: Sequence Targeting Reagents Removed from Environment. ZFIN Historical Data.
ZFIN Staff (2007) Microarray Expression to Gene Association in ZFIN. Semi-automated Curation.
ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.
ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.
ZFIN Staff (2017) Curation of PANTHER Gene IDs. Automated Data Submission.
ZFIN Staff (2020) Addition of links from ZFIN to Expression Atlas. Semi-automated Curation.
ZFIN Staff (2013) Curation of NCBI Gene Data Via Shared Vega Gene IDs. Automated Data Submission.
ZFIN Staff (2003) Curation of VEGA Database Links. Automated Data Submission.
ZFIN Staff (2024) Association of Ensembl transcripts with ZFIN genes. Semi-automated Curation.
ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.
ZFIN Staff (2022) Electronic Gene Ontology annotations created by ARBA machine learning models. Automated Data Submission.
ZFIN Staff (2020) Addition of links from ZFIN to Expression Atlas. Semi-automated Curation.
ZFIN Staff (2017) Curation of PANTHER Gene IDs. Automated Data Submission.
ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.
UniProt curators (2015) Electronic Gene Ontology annotations created by transferring manual GO annotations between related proteins based on shared sequence features.. Automated Data Submission.
ZFIN Staff (2015) Data Model Change: Sequence Targeting Reagents Removed from Environment. ZFIN Historical Data.
Busch-Nentwich, E., Kettleborough, R., Dooley, C. M., Scahill, C., Sealy, I., White, R., Herd, C., Mehroke, S., Wali, N., Carruthers, S., Hall, A., Collins, J., Gibbons, R., Pusztai, Z., Clark, R., and Stemple, D.L. (2013) Sanger Institute Zebrafish Mutation Project mutant data submission. ZFIN Direct Data Submission.
ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.
ZFIN Staff (2013) Curation of NCBI Gene Data Via Shared Vega Gene IDs. Automated Data Submission.
Busch-Nentwich, E., Kettleborough, R., Harvey, S., Collins, J., Ding, M., Dooley, C., Fenyes, F., Gibbons, R., Herd, C., Mehroke, S., Scahill, C., Sealy, I., Wali, N., White, R., and Stemple, D.L. (2012) Sanger Institute Zebrafish Mutation Project mutant, phenotype and image data submission. ZFIN Direct Data Submission.
UniProt-GOA (2012) Gene Ontology annotation based on UniPathway vocabulary mapping. Manually curated data.
Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.
ZFIN Staff (2007) Microarray Expression to Gene Association in ZFIN. Semi-automated Curation.
ZFIN Staff (2006) Curation of Ensembl Database Links. Automated Data Submission.
ZFIN Staff (2003) Curation of VEGA Database Links. Automated Data Submission.
ZFIN Staff (2003) Curation of orthology data. Manually curated data.
ZFIN Staff (2003) Gene Ontology Annotation Through Association of Enzyme Commission numbers with GO Terms. Automated Data Submission.
ZFIN Staff (2002) Gene Ontology Annotation Through Association of UniProt Keywords with GO Terms. Automated Data Submission.
ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.
ZFIN Staff (2002) Scientific Curation. Manually curated data.
ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission.
ZFIN Staff (2002) Curation of EMBL records. Automated Data Submission.
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