acacb

ID

ZDB-GENE-060526-132

Name

acetyl-CoA carboxylase beta

Symbol

acacb Nomenclature History

Previous Names

si:ch211-250o15.3

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable acetyl-CoA carboxylase activity. Predicted to be involved in fatty acid biosynthetic process. Predicted to act upstream of or within fatty acid metabolic process. Predicted to be active in mitochondrion. Is expressed in liver. Orthologous to human ACACB (acetyl-CoA carboxylase beta).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With acacb Human Ortholog

No data available

Associated With acacb Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000089	Biotin/lipoyl attachment
Domain	IPR005481	Biotin carboxylase-like, N-terminal domain
Domain	IPR005482	Biotin carboxylase, C-terminal
Domain	IPR011761	ATP-grasp fold
Domain	IPR011762	Acetyl-coenzyme A carboxyltransferase, N-terminal
Domain	IPR011763	Acetyl-coenzyme A carboxyltransferase, C-terminal
Domain	IPR011764	Biotin carboxylation domain
Domain	IPR013537	Acetyl-CoA carboxylase, central domain
Domain	IPR034733	Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta
Domain	IPR049074	Acetyl-CoA carboxylase, BT domain
Family	IPR049076	Acetyl-CoA carboxylase
Homologous_superfamily	IPR011053	Single hybrid motif
Homologous_superfamily	IPR011054	Rudiment single hybrid motif
Homologous_superfamily	IPR013815	ATP-grasp fold, subdomain 1
Homologous_superfamily	IPR016185	Pre-ATP-grasp domain superfamily
Homologous_superfamily	IPR029045	ClpP/crotonase-like domain superfamily

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:A0A8M9PYI5	InterPro	2372
UniProtKB:A0A8M9PKW2	InterPro	2386
UniProtKB:A0A8M9Q417	InterPro	2364
UniProtKB:A0AC58JNT6	InterPro	2378
UniProtKB:A0AC58JNU0	InterPro	2378
UniProtKB:A0AC58JNU1	InterPro	2386
UniProtKB:A0AC58JNU9	InterPro	2364
UniProtKB:A0AC58JNV0	InterPro	2378
UniProtKB:A0AC58JNV1	InterPro	2259
UniProtKB:A0AC58JNV2	InterPro	2281
UniProtKB:A0AC58JNV4	InterPro	2254
UniProtKB:A0AC58JNV5	InterPro	2267
UniProtKB:A0AC58JNV9	InterPro	2372
UniProtKB:A0AC58JNW0	InterPro	2262
UniProtKB:A0AC58JNW2	InterPro	2273
UniProtKB:A0AC58JNW3	InterPro	2364
UniProtKB:A0AC58JNW5	InterPro	2240
UniProtKB:A0AC58JNW7	InterPro	2372
UniProtKB:A0AC58JNX1	InterPro	2386
UniProtKB:A0AC58JNY4	InterPro	2248