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ZFIN ID:
ZDB-GENE-050310-5
CITATIONS
(63 total)
Gene Name:
insulin-like 3 (Leydig cell)
Gene Symbol:
insl3
Alnafea, H., Vahkal, B., Zelmer, C.K., Yegorov, S., Bogerd, J., Good, S.V. (2019) Japanese medaka as a model for studying the relaxin family genes involved in neuroendocrine regulation: Insights from the expression of fish-specific rln3 and insl5 and rxfp3/4-type receptor paralogues. Molecular and Cellular Endocrinology. 487:2-11
Assis, L.H., Crespo, D., Morais, R.D., França, L.R., Bogerd, J., Schulz, R.W. (2016) INSL3 stimulates spermatogonial differentiation in testis of adult zebrafish (Danio rerio). Cell and tissue research. 363(2):579-88
Chen, Y., Tang, H., Wang, L., Wei, T., Liu, X., Lin, H. (2019) New insights into the role of mTORC1 in male fertility in zebrafish. General and comparative endocrinology. 286:113306
Crespo, D., Assis, L.H., Furmanek, T., Bogerd, J., Schulz, R.W. (2016) Expression profiling identifies Sertoli and Leydig cell genes as Fsh targets in adult zebrafish testis. Molecular and Cellular Endocrinology. 437:237-251
Crespo, D., Assis, L.H.C., van de Kant, H.J.G., de Waard, S., Safian, D., Lemos, M.S., Bogerd, J., Schulz, R.W. (2019) Endocrine and local signaling interact to regulate spermatogenesis in zebrafish: Follicle-stimulating hormone, retinoic acid and androgens. Development (Cambridge, England). 146(21):
Crespo, D., Assis, L.H.C., Zhang, Y.T., Safian, D., Furmanek, T., Skaftnesmo, K.O., Norberg, B., Ge, W., Choi, Y.C., den Broeder, M.J., Legler, J., Bogerd, J., Schulz, R.W. (2021) Insulin-like 3 affects zebrafish spermatogenic cells directly and via Sertoli cells. Communications biology. 4:204
Crespo, D., Lemos, M.S., Zhang, Y.T., Safian, D., Norberg, B., Bogerd, J., Schulz, R. (2019) PGE2 inhibits spermatogonia differentiation in zebrafish: interaction with Fsh and an androgen. The Journal of endocrinology. 244(1):163-175
de Castro Assis, L.H., Nobrega, R.H., Gómez-González, N.E., Bogerd, J., Schulz, R. (2018) Estrogen-induced inhibition of spermatogenesis in zebrafish is largely reversed by androgen. Journal of molecular endocrinology. 60(4):273-284
Donizetti, A., Calicchio, M., Romano, M.Z., Rosati, L., Turco, M., Carrese, A.M., Del Gaudio, R., Ferrandino, I., Aniello, F. (2024) Expression of Insl3 Protein in Adult
Danio rerio
. International Journal of Molecular Sciences. 25(10):
Donizetti, A., Grossi, M., Pariante, P., D'Aniello, E., Izzo, G., Minucci, S., and Aniello, F. (2008) Two neuron clusters in the stem of postembryonic zebrafish brain specifically express relaxin-3 gene: First evidence of nucleus incertus in fish. Developmental Dynamics : an official publication of the American Association of Anatomists. 237(12):3864-3869
García-López, A., de Jonge, H., Nóbrega, R.H., de Waal, P.P., van Dijk, W., Hemrika, W., Taranger, G.L., Bogerd, J., and Schulz, R.W. (2010) Studies in Zebrafish Reveal Unusual Cellular Expression Patterns of Gonadotropin Receptor Messenger Ribonucleic Acids in the Testis and Unexpected Functional Differentiation of the Gonadotropins. Endocrinology. 151(5):2349-2360
Good, S., Yegorov, S., Martijn, J., Franck, J., and Bogerd, J. (2012) New insights into ligand-receptor pairing and coevolution of relaxin family peptides and their receptors in teleosts. International Journal of Evolutionary Biology. 2012:310278
Good-Avila, S.V., Yegorov, S., Harron, S., Bogerd, J., Glen, P., Ozon, J., and Wilson, B.C. (2009) Relaxin gene family in teleosts: phylogeny, syntenic mapping, selective constraint, and expression analysis. BMC Evolutionary Biology. 9:293
Hinfray, N., Nobréga, R.H., Caulier, M., Baudiffier, D., Maillot-Maréchal, E., Chadili, E., Palluel, O., Porcher, J.M., Schulz, R., and Brion, F. (2013) Cyp17a1 and Cyp19a1 in the zebrafish testis are differentially affected by oestradiol. The Journal of endocrinology. 216(3):375-388
Li, N., Oakes, J.A., Storbeck, K., Cunliffe, V.T., Krone, N. (2019) The P450 side chain cleavage enzyme Cyp11a2 facilitates steroidogenesis in zebrafish. The Journal of endocrinology. 244(2):309-321
Li, X., Zhang, F., Wu, N., Ye, D., Wang, Y., Zhang, X., Sun, Y., Zhang, Y.A. (2020) A critical role of foxp3a-positive regulatory T cells in maintaining immune homeostasis in zebrafish testis development. Journal of genetics and genomics = Yi chuan xue bao. 47(9):547-561
Liao, X., Tao, B., Zhang, X., Chen, L., Chen, J., Song, Y., Hu, W. (2023) Loss of gdnfa disrupts spermiogenesis and male courtship behavior in zebrafish. Molecular and Cellular Endocrinology. 576:112010
Ma, X., Liu, R., Ren, Z., Qi, Y., Wei, D., Shi, J., Samra, ., Yuan, C., Huang, D. (2025) High temperature induces reproductive dysfunction in male zebrafish via DNA methylation-mediated tssk6 downregulation. Ecotoxicology and environmental safety. 302:118650118650
Morais, R.D., Nóbrega, R.H., Gómez-González, N.E., Schmidt, R., Bogerd, J., França, L.R., and Schulz, R.W. (2013) Thyroid Hormone Stimulates the Proliferation of Sertoli Cells and Single Type A Spermatogonia in Adult Zebrafish (Danio rerio) Testis. Endocrinology. 154(11):4365-76
Morais, R.D.V.S., Crespo, D., Nóbrega, R.H., Lemos, M.S., van de Kant, H.J.G., de França, L.R., Male, R., Bogerd, J., Schulz, R.W. (2017) Antagonistic regulation of spermatogonial differentiation in zebrafish (Danio rerio) by Igf3 and Amh. Molecular and Cellular Endocrinology. 454:112-124
Oakes, J.A., Barnard, L., Storbeck, K.H., Cunliffe, V.T., Krone, N.P. (2020) 11β-hydroxylase loss disrupts steroidogenesis and reproductive function in zebrafish. The Journal of endocrinology. 247(2):197-212
Oakes, J.A., Li, N., Wistow, B.R.C., Griffin, A., Barnard, L., Storbeck, K.H., Cunliffe, V.T., Krone, N.P. (2019) Ferredoxin 1b deficiency leads to testis disorganization, impaired spermatogenesis and feminization in zebrafish. Endocrinology. 160(10):2401-2416
Park, J.I., Semyonov, J., Chang, C.L., Yi, W., Warren, W., and Hsu, S.Y. (2008) Origin of INSL3-mediated testicular descent in therian mammals. Genome research. 18(6):974-985
Pereiro, P., Librán-Pérez, M., Figueras, A., Novoa, B. (2020) Conserved function of zebrafish (Danio rerio) Gdf15 as a sepsis tolerance mediator. Developmental and comparative immunology. 109:103698
Rodrigues, M.S., Tovo-Neto, A., Rosa, I.F., Doretto, L.B., Fallah, H.P., Habibi, H.R., Nóbrega, R.H. (2022) Thyroid Hormones Deficiency Impairs Male Germ Cell Development: A Cross Talk Between Hypothalamic-Pituitary-Thyroid, and-Gonadal Axes in Zebrafish. Frontiers in cell and developmental biology. 10:865948
Safian, D., Morais, R.D., Bogerd, J., Schulz, R.W. (2016) Igf binding proteins protect undifferentiated spermatogonia in the zebrafish testis against excessive differentiation. Endocrinology. 157(11):4423-4433
Safian, D., Ryane, N., Bogerd, J., Schulz, R.W. (2018) Fsh stimulates Leydig cell Wnt5a production, enriching zebrafish type A spermatogonia. The Journal of endocrinology. 239:351-363
Schmid, S., Willi, R.A., Salgueiro-González, N., Fent, K. (2019) Effects of new generation progestins, including as mixtures and in combination with other classes of steroid hormones, on zebrafish early life stages. The Science of the total environment. 709:136262
Shi, W.J., Zhao, J.L., Jiang, Y.X., Huang, G.Y., Liu, Y.S., Zhang, J.N., Ying, G.G. (2017) TRANSCRIPTIONAL AND HISTOLOGICAL ALTERATIONS IN GONAD OF ADULT ZEBRAFISH AFTER EXPOSURE TO THE SYNTHETIC PROGESTIN NORGESTREL. Environmental toxicology and chemistry. 36(12):3267-3276
Shimizu, N., Matsuda, M. (2018) Identification of a Novel Zebrafish Mutant Line that Develops Testicular Germ Cell Tumors. Zebrafish. 16(1):15-28
Skaar, K.S., Nóbrega, R.H., Magaraki, A., Olsen, L.C., Schulz, R.W., and Male, R. (2011) Proteolytically Activated, Recombinant Anti-Mullerian Hormone Inhibits Androgen Secretion, Proliferation, and Differentiation of Spermatogonia in Adult Zebrafish Testis Organ Cultures. Endocrinology. 152(9):3527-40
Tang, H., Chen, Y., Liu, Y., Yin, Y., Li, G., Guo, Y., Liu, X., Lin, H. (2017) New Insights Into the Role of Estrogens in Male Fertility Based on Findings in Aromatase-Deficient Zebrafish. Endocrinology. 158:3042-3054
Tang, H., Chen, Y., Wang, L., Yin, Y., Li, G., Guo, Y., Liu, Y., Lin, H., Cheng, C.H.K., Liu, X. (2017) Fertility impairment with defective spermatogenesis and steroidogenesis in male zebrafish lacking androgen receptor. Biology of reproduction. 98(2):227-238
Wang, X., Zhu, J., Wang, H., Deng, W., Jiao, S., Wang, Y., He, M., Zhang, F., Liu, T., Hao, Y., Ye, D., Sun, Y. (2023) Induced formation of primordial germ cells from zebrafish blastomeres by germplasm factors. Nature communications. 14:79187918
Wang, Y., Ye, D., Zhang, F., Zhang, R., Zhu, J., Wang, H., He, M., Sun, Y. (2021) Cyp11a2 is essential for oocyte development and spermatogonial stem cell differentiation in zebrafish. Endocrinology. 163(2):
Wilkinson, T.N., Speed, T.P., Tregear, G.W., and Bathgate, R.A. (2005) Evolution of the relaxin-like peptide family. BMC Evolutionary Biology. 5(1):14
Wilson, B.C., Burnett, D., Rappaport, R., Parry, L.J., and Fletcher, E.K. (2009) Relaxin-3 and RXFP3 expression, and steroidogenic actions in the ovary of teleost fish. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. 153(1):69-74
Yegorov, S., Good-Avila, S.V., Parry, L., and Wilson, B.C. (2009) Relaxin family genes in humans and teleosts. Annals of the New York Academy of Sciences. 1160:42-44
Zanardini, M., Zhang, W., Habibi, H.R. (2024) Arginine Vasotocin Directly Regulates Spermatogenesis in Adult Zebrafish (
Danio rerio
) Testes. International Journal of Molecular Sciences. 25(12):
Zhai, G., Shu, T., Xia, Y., Lu, Y., Shang, G., Jin, X., He, J., Nie, P., Yin, Z. (2018) Characterization of sexual trait development in cyp17a1-deficient zebrafish. Endocrinology. 159(10):3549-3562
Zhai, G., Shu, T., Yu, G., Tang, H., Shi, C., Jia, J., Lou, Q., Dai, X., Jin, X., He, J., Xiao, W., Liu, X., Yin, Z. (2022) Augmentation of progestin signaling rescues testis organization and spermatogenesis in zebrafish with the depletion of androgen signaling. eLIFE. 11:
Zhang, Q., Ye, D., Wang, H., Wang, Y., Sun, Y. (2020) Zebrafish cyp11c1 knockout reveals the roles of 11-ketotestosterone and cortisol in sexual development and reproduction. Endocrinology. 161(6):
Zhang, R., Tu, Y.X., Ye, D., Gu, Z., Chen, Z.X., Sun, Y. (2022) A Germline-Specific Regulator of Mitochondrial Fusion is Required for Maintenance and Differentiation of Germline Stem and Progenitor Cells. Advanced science (Weinheim, Baden-Wurttemberg, Germany). 9(36):e2203631
Zhang, Y., Zhou, Y., Tang, Q., Hu, F., Feng, L., Shen, J., Huang, B. (2018) The protective effects of selenium-enriched spirulina on the reproductive system of male zebrafish (Danio rerio) exposed to beta-cypermethrin. Food & function. 9(11):5791-5804
Zucchi, S., Castiglioni, S., and Fent, K. (2013) Progesterone Alters Global Transcription Profiles at Environmental Concentrations in Brain and Ovary of Female Zebrafish (Danio rerio). Environmental science & technology. 47(21):12548-56
Ma, X., Liu, R., Ren, Z., Qi, Y., Wei, D., Shi, J., Samra, ., Yuan, C., Huang, D. (2025) High temperature induces reproductive dysfunction in male zebrafish via DNA methylation-mediated tssk6 downregulation. Ecotoxicology and environmental safety. 302:118650118650
Donizetti, A., Calicchio, M., Romano, M.Z., Rosati, L., Turco, M., Carrese, A.M., Del Gaudio, R., Ferrandino, I., Aniello, F. (2024) Expression of Insl3 Protein in Adult
Danio rerio
. International Journal of Molecular Sciences. 25(10):
Zanardini, M., Zhang, W., Habibi, H.R. (2024) Arginine Vasotocin Directly Regulates Spermatogenesis in Adult Zebrafish (
Danio rerio
) Testes. International Journal of Molecular Sciences. 25(12):
Liao, X., Tao, B., Zhang, X., Chen, L., Chen, J., Song, Y., Hu, W. (2023) Loss of gdnfa disrupts spermiogenesis and male courtship behavior in zebrafish. Molecular and Cellular Endocrinology. 576:112010
Wang, X., Zhu, J., Wang, H., Deng, W., Jiao, S., Wang, Y., He, M., Zhang, F., Liu, T., Hao, Y., Ye, D., Sun, Y. (2023) Induced formation of primordial germ cells from zebrafish blastomeres by germplasm factors. Nature communications. 14:79187918
Rodrigues, M.S., Tovo-Neto, A., Rosa, I.F., Doretto, L.B., Fallah, H.P., Habibi, H.R., Nóbrega, R.H. (2022) Thyroid Hormones Deficiency Impairs Male Germ Cell Development: A Cross Talk Between Hypothalamic-Pituitary-Thyroid, and-Gonadal Axes in Zebrafish. Frontiers in cell and developmental biology. 10:865948
Zhai, G., Shu, T., Yu, G., Tang, H., Shi, C., Jia, J., Lou, Q., Dai, X., Jin, X., He, J., Xiao, W., Liu, X., Yin, Z. (2022) Augmentation of progestin signaling rescues testis organization and spermatogenesis in zebrafish with the depletion of androgen signaling. eLIFE. 11:
Zhang, R., Tu, Y.X., Ye, D., Gu, Z., Chen, Z.X., Sun, Y. (2022) A Germline-Specific Regulator of Mitochondrial Fusion is Required for Maintenance and Differentiation of Germline Stem and Progenitor Cells. Advanced science (Weinheim, Baden-Wurttemberg, Germany). 9(36):e2203631
Crespo, D., Assis, L.H.C., Zhang, Y.T., Safian, D., Furmanek, T., Skaftnesmo, K.O., Norberg, B., Ge, W., Choi, Y.C., den Broeder, M.J., Legler, J., Bogerd, J., Schulz, R.W. (2021) Insulin-like 3 affects zebrafish spermatogenic cells directly and via Sertoli cells. Communications biology. 4:204
Wang, Y., Ye, D., Zhang, F., Zhang, R., Zhu, J., Wang, H., He, M., Sun, Y. (2021) Cyp11a2 is essential for oocyte development and spermatogonial stem cell differentiation in zebrafish. Endocrinology. 163(2):
Li, X., Zhang, F., Wu, N., Ye, D., Wang, Y., Zhang, X., Sun, Y., Zhang, Y.A. (2020) A critical role of foxp3a-positive regulatory T cells in maintaining immune homeostasis in zebrafish testis development. Journal of genetics and genomics = Yi chuan xue bao. 47(9):547-561
Oakes, J.A., Barnard, L., Storbeck, K.H., Cunliffe, V.T., Krone, N.P. (2020) 11β-hydroxylase loss disrupts steroidogenesis and reproductive function in zebrafish. The Journal of endocrinology. 247(2):197-212
Pereiro, P., Librán-Pérez, M., Figueras, A., Novoa, B. (2020) Conserved function of zebrafish (Danio rerio) Gdf15 as a sepsis tolerance mediator. Developmental and comparative immunology. 109:103698
Zhang, Q., Ye, D., Wang, H., Wang, Y., Sun, Y. (2020) Zebrafish cyp11c1 knockout reveals the roles of 11-ketotestosterone and cortisol in sexual development and reproduction. Endocrinology. 161(6):
Alnafea, H., Vahkal, B., Zelmer, C.K., Yegorov, S., Bogerd, J., Good, S.V. (2019) Japanese medaka as a model for studying the relaxin family genes involved in neuroendocrine regulation: Insights from the expression of fish-specific rln3 and insl5 and rxfp3/4-type receptor paralogues. Molecular and Cellular Endocrinology. 487:2-11
Chen, Y., Tang, H., Wang, L., Wei, T., Liu, X., Lin, H. (2019) New insights into the role of mTORC1 in male fertility in zebrafish. General and comparative endocrinology. 286:113306
Crespo, D., Assis, L.H.C., van de Kant, H.J.G., de Waard, S., Safian, D., Lemos, M.S., Bogerd, J., Schulz, R.W. (2019) Endocrine and local signaling interact to regulate spermatogenesis in zebrafish: Follicle-stimulating hormone, retinoic acid and androgens. Development (Cambridge, England). 146(21):
Crespo, D., Lemos, M.S., Zhang, Y.T., Safian, D., Norberg, B., Bogerd, J., Schulz, R. (2019) PGE2 inhibits spermatogonia differentiation in zebrafish: interaction with Fsh and an androgen. The Journal of endocrinology. 244(1):163-175
Li, N., Oakes, J.A., Storbeck, K., Cunliffe, V.T., Krone, N. (2019) The P450 side chain cleavage enzyme Cyp11a2 facilitates steroidogenesis in zebrafish. The Journal of endocrinology. 244(2):309-321
Oakes, J.A., Li, N., Wistow, B.R.C., Griffin, A., Barnard, L., Storbeck, K.H., Cunliffe, V.T., Krone, N.P. (2019) Ferredoxin 1b deficiency leads to testis disorganization, impaired spermatogenesis and feminization in zebrafish. Endocrinology. 160(10):2401-2416
Schmid, S., Willi, R.A., Salgueiro-González, N., Fent, K. (2019) Effects of new generation progestins, including as mixtures and in combination with other classes of steroid hormones, on zebrafish early life stages. The Science of the total environment. 709:136262
de Castro Assis, L.H., Nobrega, R.H., Gómez-González, N.E., Bogerd, J., Schulz, R. (2018) Estrogen-induced inhibition of spermatogenesis in zebrafish is largely reversed by androgen. Journal of molecular endocrinology. 60(4):273-284
Safian, D., Ryane, N., Bogerd, J., Schulz, R.W. (2018) Fsh stimulates Leydig cell Wnt5a production, enriching zebrafish type A spermatogonia. The Journal of endocrinology. 239:351-363
Shimizu, N., Matsuda, M. (2018) Identification of a Novel Zebrafish Mutant Line that Develops Testicular Germ Cell Tumors. Zebrafish. 16(1):15-28
Zhai, G., Shu, T., Xia, Y., Lu, Y., Shang, G., Jin, X., He, J., Nie, P., Yin, Z. (2018) Characterization of sexual trait development in cyp17a1-deficient zebrafish. Endocrinology. 159(10):3549-3562
Zhang, Y., Zhou, Y., Tang, Q., Hu, F., Feng, L., Shen, J., Huang, B. (2018) The protective effects of selenium-enriched spirulina on the reproductive system of male zebrafish (Danio rerio) exposed to beta-cypermethrin. Food & function. 9(11):5791-5804
Morais, R.D.V.S., Crespo, D., Nóbrega, R.H., Lemos, M.S., van de Kant, H.J.G., de França, L.R., Male, R., Bogerd, J., Schulz, R.W. (2017) Antagonistic regulation of spermatogonial differentiation in zebrafish (Danio rerio) by Igf3 and Amh. Molecular and Cellular Endocrinology. 454:112-124
Shi, W.J., Zhao, J.L., Jiang, Y.X., Huang, G.Y., Liu, Y.S., Zhang, J.N., Ying, G.G. (2017) TRANSCRIPTIONAL AND HISTOLOGICAL ALTERATIONS IN GONAD OF ADULT ZEBRAFISH AFTER EXPOSURE TO THE SYNTHETIC PROGESTIN NORGESTREL. Environmental toxicology and chemistry. 36(12):3267-3276
Tang, H., Chen, Y., Liu, Y., Yin, Y., Li, G., Guo, Y., Liu, X., Lin, H. (2017) New Insights Into the Role of Estrogens in Male Fertility Based on Findings in Aromatase-Deficient Zebrafish. Endocrinology. 158:3042-3054
Tang, H., Chen, Y., Wang, L., Yin, Y., Li, G., Guo, Y., Liu, Y., Lin, H., Cheng, C.H.K., Liu, X. (2017) Fertility impairment with defective spermatogenesis and steroidogenesis in male zebrafish lacking androgen receptor. Biology of reproduction. 98(2):227-238
Assis, L.H., Crespo, D., Morais, R.D., França, L.R., Bogerd, J., Schulz, R.W. (2016) INSL3 stimulates spermatogonial differentiation in testis of adult zebrafish (Danio rerio). Cell and tissue research. 363(2):579-88
Crespo, D., Assis, L.H., Furmanek, T., Bogerd, J., Schulz, R.W. (2016) Expression profiling identifies Sertoli and Leydig cell genes as Fsh targets in adult zebrafish testis. Molecular and Cellular Endocrinology. 437:237-251
Safian, D., Morais, R.D., Bogerd, J., Schulz, R.W. (2016) Igf binding proteins protect undifferentiated spermatogonia in the zebrafish testis against excessive differentiation. Endocrinology. 157(11):4423-4433
Hinfray, N., Nobréga, R.H., Caulier, M., Baudiffier, D., Maillot-Maréchal, E., Chadili, E., Palluel, O., Porcher, J.M., Schulz, R., and Brion, F. (2013) Cyp17a1 and Cyp19a1 in the zebrafish testis are differentially affected by oestradiol. The Journal of endocrinology. 216(3):375-388
Morais, R.D., Nóbrega, R.H., Gómez-González, N.E., Schmidt, R., Bogerd, J., França, L.R., and Schulz, R.W. (2013) Thyroid Hormone Stimulates the Proliferation of Sertoli Cells and Single Type A Spermatogonia in Adult Zebrafish (Danio rerio) Testis. Endocrinology. 154(11):4365-76
Zucchi, S., Castiglioni, S., and Fent, K. (2013) Progesterone Alters Global Transcription Profiles at Environmental Concentrations in Brain and Ovary of Female Zebrafish (Danio rerio). Environmental science & technology. 47(21):12548-56
Good, S., Yegorov, S., Martijn, J., Franck, J., and Bogerd, J. (2012) New insights into ligand-receptor pairing and coevolution of relaxin family peptides and their receptors in teleosts. International Journal of Evolutionary Biology. 2012:310278
Skaar, K.S., Nóbrega, R.H., Magaraki, A., Olsen, L.C., Schulz, R.W., and Male, R. (2011) Proteolytically Activated, Recombinant Anti-Mullerian Hormone Inhibits Androgen Secretion, Proliferation, and Differentiation of Spermatogonia in Adult Zebrafish Testis Organ Cultures. Endocrinology. 152(9):3527-40
García-López, A., de Jonge, H., Nóbrega, R.H., de Waal, P.P., van Dijk, W., Hemrika, W., Taranger, G.L., Bogerd, J., and Schulz, R.W. (2010) Studies in Zebrafish Reveal Unusual Cellular Expression Patterns of Gonadotropin Receptor Messenger Ribonucleic Acids in the Testis and Unexpected Functional Differentiation of the Gonadotropins. Endocrinology. 151(5):2349-2360
Good-Avila, S.V., Yegorov, S., Harron, S., Bogerd, J., Glen, P., Ozon, J., and Wilson, B.C. (2009) Relaxin gene family in teleosts: phylogeny, syntenic mapping, selective constraint, and expression analysis. BMC Evolutionary Biology. 9:293
Wilson, B.C., Burnett, D., Rappaport, R., Parry, L.J., and Fletcher, E.K. (2009) Relaxin-3 and RXFP3 expression, and steroidogenic actions in the ovary of teleost fish. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. 153(1):69-74
Yegorov, S., Good-Avila, S.V., Parry, L., and Wilson, B.C. (2009) Relaxin family genes in humans and teleosts. Annals of the New York Academy of Sciences. 1160:42-44
Donizetti, A., Grossi, M., Pariante, P., D'Aniello, E., Izzo, G., Minucci, S., and Aniello, F. (2008) Two neuron clusters in the stem of postembryonic zebrafish brain specifically express relaxin-3 gene: First evidence of nucleus incertus in fish. Developmental Dynamics : an official publication of the American Association of Anatomists. 237(12):3864-3869
Park, J.I., Semyonov, J., Chang, C.L., Yi, W., Warren, W., and Hsu, S.Y. (2008) Origin of INSL3-mediated testicular descent in therian mammals. Genome research. 18(6):974-985
Wilkinson, T.N., Speed, T.P., Tregear, G.W., and Bathgate, R.A. (2005) Evolution of the relaxin-like peptide family. BMC Evolutionary Biology. 5(1):14
Additional Citations (18):
Busch-Nentwich, E., Kettleborough, R., Dooley, C. M., Scahill, C., Sealy, I., White, R., Herd, C., Mehroke, S., Wali, N., Carruthers, S., Hall, A., Collins, J., Gibbons, R., Pusztai, Z., Clark, R., and Stemple, D.L. (2013) Sanger Institute Zebrafish Mutation Project mutant data submission. ZFIN Direct Data Submission.
Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.
GOA curators, UniProt curators (2007) Gene Ontology annotation based on Swiss-Prot Subcellular Location vocabulary mapping. Manually curated data.
UniProt-GOA (2011) Gene Ontology annotation based on the automatic assignment of UniProtKB Subcellular Location terms in UniProtKB/TrEMBL entries. Manually curated data.
Zebrafish Nomenclature Committee (2003) Nomenclature Data Curation (2003-2010). Nomenclature Committee Submission.
Zebrafish Nomenclature Committee (2020) Nomenclature Data Curation (2020). Nomenclature Committee Submission.
Zebrafish Nomenclature Committee (2021) Nomenclature Data Curation (2021). Nomenclature Committee Submission.
ZFIN Staff (2006) Curation of Ensembl Database Links. Automated Data Submission.
ZFIN Staff (2003) Curation of orthology data. Manually curated data.
ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.
ZFIN Staff (2003) Curation of unpublished nucleotide sequence accession numbers. Manually curated data.
ZFIN Staff (2017) Curation of PANTHER Gene IDs. Automated Data Submission.
ZFIN Staff (2003) Curation of VEGA Database Links. Automated Data Submission.
ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.
ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission.
ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.
ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.
ZFIN Staff (2020) Addition of links from ZFIN to Expression Atlas. Semi-automated Curation.
ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.
Zebrafish Nomenclature Committee (2021) Nomenclature Data Curation (2021). Nomenclature Committee Submission.
Zebrafish Nomenclature Committee (2020) Nomenclature Data Curation (2020). Nomenclature Committee Submission.
ZFIN Staff (2020) Addition of links from ZFIN to Expression Atlas. Semi-automated Curation.
ZFIN Staff (2017) Curation of PANTHER Gene IDs. Automated Data Submission.
ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.
Busch-Nentwich, E., Kettleborough, R., Dooley, C. M., Scahill, C., Sealy, I., White, R., Herd, C., Mehroke, S., Wali, N., Carruthers, S., Hall, A., Collins, J., Gibbons, R., Pusztai, Z., Clark, R., and Stemple, D.L. (2013) Sanger Institute Zebrafish Mutation Project mutant data submission. ZFIN Direct Data Submission.
ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.
UniProt-GOA (2011) Gene Ontology annotation based on the automatic assignment of UniProtKB Subcellular Location terms in UniProtKB/TrEMBL entries. Manually curated data.
Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.
GOA curators, UniProt curators (2007) Gene Ontology annotation based on Swiss-Prot Subcellular Location vocabulary mapping. Manually curated data.
ZFIN Staff (2006) Curation of Ensembl Database Links. Automated Data Submission.
Zebrafish Nomenclature Committee (2003) Nomenclature Data Curation (2003-2010). Nomenclature Committee Submission.
ZFIN Staff (2003) Curation of VEGA Database Links. Automated Data Submission.
ZFIN Staff (2003) Curation of orthology data. Manually curated data.
ZFIN Staff (2003) Curation of unpublished nucleotide sequence accession numbers. Manually curated data.
ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.
ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission.
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