ZFIN

ZFIN ID: ZDB-GENE-030728-3

ZFIN ID: ZDB-GENE-030728-3

CITATIONS (58 total)

Gene Name:	progestin and adipoQ receptor family member VIII
Gene Symbol:	paqr8

Uju, C., Unniappan, S. (2025) Brain Derived Neurotrophic Factor Promotes Oocyte Maturation Through the TrkB-MAPk-PI3K Pathway in Zebrafish. Molecular and Cellular Endocrinology. :112703112703

Uju, C., Karimzadeh, K., Unniappan, S. (2024) Brain Derived Neurotrophic Factor Stimulates Hypothalamic and Gonadal Reproductive Hormones and Oocyte Maturation in Zebrafish. Reproduction (Cambridge, England). 169(1):

Tsakoumis, E., Ahi, E.P., Schmitz, M. (2022) Impaired leptin signaling causes subfertility in female zebrafish. Molecular and Cellular Endocrinology. 546:111595

Hou, L., Chen, S., Shi, W., Chen, H., Liang, Y., Wang, X., Tan, J., Wang, Y., Deng, X., Zhan, M., Long, J., Cai, G., Luo, S., Zhang, C., Liu, J., Leung, J.Y.S., Xie, L. (2020) Norethindrone alters mating behaviors, ovary histology, hormone production and transcriptional expression of steroidogenic genes in zebrafish (Danio rerio). Ecotoxicology and environmental safety. 195:110496

Li, M., Cao, J., Zhao, Y., Wu, P., Li, X., Khodaei, F., Han, Y., Wang, J. (2020) Fluoride impairs ovary development by affecting oogenesis and inducing oxidative stress and apoptosis in female zebrafish (Danio rerio). Chemosphere. 256:127105

Lu, H., Zhao, C., Zhu, B., Zhang, Z., Ge, W. (2020) Loss of Inhibin Advances Follicle Activation and Female Puberty Onset but Blocks Oocyte Maturation in Zebrafish. Endocrinology. 161(12):

Maradonna, F., Gioacchini, G., Notarstefano, V., Fontana, C.M., Citton, F., Dalla Valle, L., Giorgini, E., Carnevali, O. (2020) Knockout of the Glucocorticoid Receptor Impairs Reproduction in Female Zebrafish. International Journal of Molecular Sciences. 21(23):

Wu, X.J., Liu, D.T., Chen, S., Hong, W., Zhu, Y. (2020) Impaired oocyte maturation and ovulation in membrane progestin receptor (mPR) knockouts in zebrafish. Molecular and Cellular Endocrinology. 511:110856

Zayed, Y., Malik, R., Qi, X., Peng, C. (2020) Nodal regulates ovarian functions in zebrafish. Molecular and Cellular Endocrinology. 511:110821

Liang, Y.Q., Huang, G.Y., Zhen, Z., Tian, F., Hou, L., Lin, Z., Ying, G.G. (2019) The effects of binary mixtures of estradiol and progesterone on transcriptional expression profiles of genes involved in hypothalamic-pituitary-gonadal axis and circadian rhythm signaling in embryonic zebrafish (Danio rerio). Ecotoxicology and environmental safety. 174:540-548

Santangeli, S., Consales, C., Pacchierotti, F., Habibi, H.R., Carnevali, O. (2019) Transgenerational effects of BPA on female reproduction. The Science of the total environment. 685:1294-1305

Wu, X.J., Jermaul Williams, M., Rameshkumar Patel, P., Ann Kew, K., Zhu, Y. (2019) Subfertility and reduced progestin synthesis in Pgrmc2 knockout zebrafish. General and comparative endocrinology. 282:113218

Wu, X.J., Zhu, Y. (2019) Downregulation of nuclear progestin receptor (Pgr) and subfertility in double knockouts of progestin receptor membrane component 1 (pgrmc1) and pgrmc2 in zebrafish. General and comparative endocrinology. 285:113275

Zhang, H., Chen, Z.F., Qi, Z., Yan, S.C., Wei, W.W., Liu, G., Cai, Z. (2019) ANALYSIS OF TRANSCRIPTIONAL RESPONSE IN ZEBRAFISH ELEUTHEROEMBRYOS EXPOSED TO CLIMBAZOLE: SIGNALING PATHWAYS AND POTENTIAL BIOMARKERS. Environmental toxicology and chemistry. 38(4):794-805

Liang, Y.Q., Huang, G.Y., Zhao, J.L., Shi, W.J., Hu, L.X., Tian, F., Liu, S.S., Jiang, Y.X., Ying, G.G. (2017) Transcriptional alterations induced by binary mixtures of ethinylestradiol and norgestrel during the early development of zebrafish (Danio rerio). Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 195:60-67

Santangeli, S., Maradonna, F., Zanardini, M., Notarstefano, V., Gioacchini, G., Forner-Piquer, I., Habibi, H., Carnevali, O. (2017) Effects of diisononyl phthalate on Danio rerio reproduction. Environmental pollution (Barking, Essex : 1987). 231:1051-1062

Yumnamcha, T., Khan, Z.A., Rajiv, C., Devi, S.D., Mondal, G., Sanjita Devi, H., Bharali, R., Chattoraj, A. (2017) Interaction of melatonin and gonadotropin-inhibitory hormone on the zebrafish brain-pituitary-reproductive axis. Molecular reproduction and development. 84(5):389-400

Qi, X., Salem, M., Zhou, W., Sato-Shimizu, M., Ye, G., Smitz, J., Peng, C. (2016) Neurokinin B Exerts Direct Effects on the Ovary to Stimulate Estradiol Production. Endocrinology. 157:3355-65

Santangeli, S., Maradonna, F., Gioacchini, G., Cobellis, G., Piccinetti, C.C., Dalla Valle, L., Carnevali, O. (2016) BPA-Induced Deregulation Of Epigenetic Patterns: Effects On Female Zebrafish Reproduction. Scientific Reports. 6:21982

Tang, H., Liu, Y., Li, J., Yin, Y., Li, G., Chen, Y., Li, S., Zhang, Y., Lin, H., Liu, X., Cheng, C.H. (2016) Gene knockout of nuclear progesterone receptor provides insights into the regulation of ovulation by LH signaling in zebrafish. Scientific Reports. 6:28545

Saraiva, L.R., Ahuja, G., Ivandic, I., Syed, A.S., Marioni, J.C., Korsching, S.I., Logan, D.W. (2015) Molecular and neuronal homology between the olfactory systems of zebrafish and mouse. Scientific Reports. 5:11487

Zhao, Y., Castiglioni, S., Fent, K. (2015) Synthetic progestins medroxyprogesterone acetate and dydrogesterone and their binary mixtures adversely affect reproduction and lead to histological and transcriptional alterations in zebrafish (Danio rerio). Environmental science & technology. 49(7):4636-45

Zhao, Y., Xie, L., Yan, Y. (2015) Microcystin-LR impairs zebrafish reproduction by affecting oogenesis and endocrine system. Chemosphere. 120C:115-122

Chu, L., Li, J., Liu, Y., Hu, W., Cheng, C.H. (2014) Targeted gene disruption in zebrafish reveals noncanonical functions of Lh signaling in reproduction. Molecular endocrinology (Baltimore, Md.). 28(11):1785-95

Han, J., Wang, Q., Wang, X., Li, Y., Wen, S., Liu, S., Ying, G., Guo, Y., Zhou, B. (2014) The synthetic progestin megestrol acetate adversely affects zebrafish reproduction. Aquatic toxicology (Amsterdam, Netherlands). 150:66-72

Lu, X., Yu, R.M., Murphy, M.B., Lau, K., Wu, R.S. (2014) Hypoxia disrupts gene modulation along the brain-pituitary-gonad (BPG)-liver axis. Ecotoxicology and environmental safety. 102:70-8

Carnevali, O., Avella, M.A., and Gioacchini, G. (2013) Effects of probiotic administration on zebrafish development and reproduction. General and comparative endocrinology. 188:297-302

Gioacchini, G., Giorgini, E., Merrifield, D.L., Hardiman, G., Borini, A., Vaccari, L., and Carnevali, O. (2012) Probiotics Can Induce Follicle Maturational Competence: The Danio rerio Case. Biology of reproduction. 86(3):65

Hanna, R.N., and Zhu, Y. (2011) Controls of meiotic signaling by membrane or nuclear progestin receptor in zebrafish follicle-enclosed oocytes. Molecular and Cellular Endocrinology. 337(1-2):80-8

Carnevali, O., Tosti, L., Speciale, C., Peng, C., Zhu, Y., and Maradonna, F. (2010) DEHP Impairs Zebrafish Reproduction by Affecting Critical Factors in Oogenesis. PLoS One. 5(4):e10201

Gioacchini, G., Maradonna, F., Lombardo, F., Bizzaro, D., Olivotto, I., and Carnevali, O. (2010) Increase of fecundity by probiotic administration in zebrafish (Danio rerio). Reproduction (Cambridge, England). 140(6):953-959

Pikulkaew, S., De Nadai, A., Belvedere, P., Colombo, L., and Dalla Valle, L. (2010) Expression analysis of steroid hormone receptor mRNAs during zebrafish embryogenesis. General and comparative endocrinology. 165(2):215-220

Hanna, R.N., and Zhu, Y. (2009) Expression of membrane progestin receptors in zebrafish (Danio rerio) oocytes, testis and pituitary. General and comparative endocrinology. 161(1):153-157

Tan, Q., Zagrodny, A., Bernaudo, S., and Peng, C. (2009) Regulation of membrane progestin receptors in the zebrafish ovary by gonadotropin, activin, TGF-beta and BMP-15. Molecular and Cellular Endocrinology. 312(1-2):72-79

Kolmakov, N.N., Kube, M., Reinhardt, R., and Canario, A.V. (2008) Analysis of the goldfish Carassius auratus olfactory epithelium transcriptome reveals the presence of numerous non-olfactory GPCR and putative receptors for progestin pheromones. BMC Genomics. 9:429

Hanna, R., Pang, Y., Thomas, P., and Zhu, Y. (2006) Cell-surface expression, progestin binding, and rapid nongenomic signaling of zebrafish membrane progestin receptors {alpha} and {beta} in transfected cells. The Journal of endocrinology. 190(2):247-260

Kazeto, Y., Goto-Kazeto, R., and Trant, J.M. (2005) Membrane-bound progestin receptors in channel catfish and zebrafish ovary: Changes in gene expression associated with the reproductive cycles and hormonal reagents. General and comparative endocrinology. 142(1-2):204-211

Kohli, G., Clelland, E., and Peng, C. (2005) Potential targets of transforming growth factor-beta1 during inhibition of oocyte maturation in zebrafish. Reproductive Biology and Endocrinolgy. 3:53

Zhu, Y., Bond, J., and Thomas, P. (2003) Identification, classification, and partial characterization of genes in humans and other vertebrates homologous to a fish membrane progestin receptor. Proceedings of the National Academy of Sciences of the United States of America. 100(5):2237-2242

Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903

Additional Citations (18):

ZFIN Staff (2024) Association of Ensembl transcripts with ZFIN genes. Semi-automated Curation.

ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.

ZFIN Staff (2020) Addition of links from ZFIN to Expression Atlas. Semi-automated Curation.

ZFIN Staff (2017) Curation of PANTHER Gene IDs. Automated Data Submission.

ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.

ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.

UniProt-GOA (2011) Gene Ontology annotation based on the automatic assignment of UniProtKB Subcellular Location terms in UniProtKB/TrEMBL entries. Manually curated data.

Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.

ZFIN Staff (2007) Microarray Expression to Gene Association in ZFIN. Semi-automated Curation.

ZFIN Staff (2006) Curation of Ensembl Database Links. Automated Data Submission.

Thisse, B., Thisse, C. (2004) Fast Release Clones: A High Throughput Expression Analysis. ZFIN Direct Data Submission.

ZFIN Staff (2004) ZGC Data Curation and Association in ZFIN by ZFIN Staff. Semi-automated Curation.

Zebrafish Nomenclature Committee (2003) Nomenclature Data Curation (2003-2010). Nomenclature Committee Submission.

ZFIN Staff (2003) Curation of VEGA Database Links. Automated Data Submission.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of UniProt Keywords with GO Terms. Automated Data Submission.

ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission.

ZFIN Staff (2002) Curation of EMBL records. Automated Data Submission.