ZFIN

ZFIN ID: ZDB-GENE-030616-558

ZFIN ID: ZDB-GENE-030616-558

CITATIONS (46 total)

Gene Name:	polycystic kidney disease 2-like 1
Gene Symbol:	pkd2l1

Barnaby, W., O'Malley, S., Downes, G.B. (2025) GABA _A α4 is expressed in cerebrospinal fluid-contacting neurons and regulates swim behavior in developing zebrafish. microPublication. Biology. 2025:

Epting, D., Devane, J., Mertes, R., Kayser, S., Helmstädter, M., Metzger, P., Boerries, M., Bergmann, C., Ott, E. (2025) Tulp3 deficiency results in ciliopathy phenotypes during zebrafish embryogenesis. Scientific Reports. 15:32435

Tian, G., Huang, L., Xu, Z., Lu, C., Yuan, W., Wu, Y., Liao, Z., Gao, J., Luo, Q., Cheng, B., Liao, X., Lu, H. (2025) C-mannosyltransferase DPY19L1L-mediated Reissner Fiber formation is critical for zebrafish (Danio rerio) body axis straightening. Science advances. 11:eadv2032

Marie-Hardy, L., Slimani, L., Messa, G., El Bourakkadi, Z., Prigent, A., Sayetta, C., Koëth, F., Pascal-Moussellard, H., Wyart, C., Cantaut-Belarif, Y. (2023) Loss of CSF-contacting neuron sensory function is associated with a hyper-kyphosis of the spine reminiscent of Scheuermann's disease. Scientific Reports. 13:5529

Prendergast, A.E., Jim, K.K., Marnas, H., Desban, L., Quan, F.B., Djenoune, L., Laghi, V., Hocquemiller, A., Lunsford, E.T., Roussel, J., Keiser, L., Lejeune, F.X., Dhanasekar, M., Bardet, P.L., Levraud, J.P., van de Beek, D., Vandenbroucke-Grauls, C.M.J.E., Wyart, C. (2023) CSF-contacting neurons respond to Streptococcus pneumoniae and promote host survival during central nervous system infection. Current biology : CB. 33(5):940-956.e10

Bearce, E.A., Irons, Z.H., O'Hara-Smith, J.R., Kuhns, C.J., Fisher, S.I., Crow, W.E., Grimes, D.T. (2022) Urotensin II-related peptides, Urp1 and Urp2, control zebrafish spine morphology. eLIFE. 11:

Mukaigasa, K., Sakuma, C., Yaginuma, H. (2021) The developmental hourglass model is applicable to the spinal cord based on single-cell transcriptomes and non-conserved cis-regulatory elements. Development, growth & differentiation. 63(7):372-391

Cantaut-Belarif, Y., Orts Del'Immagine, A., Penru, M., Pézeron, G., Wyart, C., Bardet, P.L. (2020) Adrenergic activation modulates the signal from the Reissner fiber to cerebrospinal fluid-contacting neurons during development. eLIFE. 9:

Jedrychowska, J., Gasanov, E.V., Korzh, V. (2020) Kcnb1 plays a role in development of the inner ear. Developmental Biology. 471:65-75

Lu, H., Shagirova, A., Goggi, J.L., Yeo, H.L., Roy, S. (2020) Reissner fibre-induced urotensin signalling from cerebrospinal fluid-contacting neurons prevents scoliosis of the vertebrate spine. Biology Open. 9(5):

Orts-Del'Immagine, A., Cantaut-Belarif, Y., Thouvenin, O., Roussel, J., Baskaran, A., Langui, D., Koëth, F., Bivas, P., Lejeune, F.X., Bardet, P.L., Wyart, C. (2020) Sensory Neurons Contacting the Cerebrospinal Fluid Require the Reissner Fiber to Detect Spinal Curvature In Vivo. Current biology : CB. 30(5):827-839.e4

Wang, X., Wang, S., Meng, Z., Zhao, C. (2020) Adrb1 and Adrb2b are the major β-adrenergic receptors regulating body axis straightening in zebrafish. Journal of genetics and genomics = Yi chuan xue bao. 47(12):781-784

Di Bella, D.J., Carcagno, A.L., Bartolomeu, M.L., Pardi, M.B., Löhr, H., Siegel, N., Hammerschmidt, M., Marín-Burgin, A., Lanuza, G.M. (2019) Ascl1 Balances Neuronal versus Ependymal Fate in the Spinal Cord Central Canal. Cell Reports. 28:2264-2274.e3

Fouchécourt, S., Picolo, F., Elis, S., Lécureuil, C., Thélie, A., Govoroun, M., Brégeon, M., Papillier, P., Lareyre, J.J., Monget, P. (2019) An evolutionary approach to recover genes predominantly expressed in the testes of the zebrafish, chicken and mouse. BMC Evolutionary Biology. 19:137

Andrzejczuk, L.A., Banerjee, S., England, S.J., Voufo, C., Kamara, K., Lewis, K.E. (2018) Tal1, Gata2a, and Gata3 Have Distinct Functions in the Development of V2b and Cerebrospinal Fluid-Contacting KA Spinal Neurons. Frontiers in neuroscience. 12:170

Sternberg, J.R., Prendergast, A.E., Brosse, L., Cantaut-Belarif, Y., Thouvenin, O., Orts-Del'Immagine, A., Castillo, L., Djenoune, L., Kurisu, S., McDearmid, J.R., Bardet, P.L., Boccara, C., Okamoto, H., Delmas, P., Wyart, C. (2018) Pkd2l1 is required for mechanoception in cerebrospinal fluid-contacting neurons and maintenance of spine curvature. Nature communications. 9:3804

Zhang, X., Jia, S., Chen, Z., Chong, Y.L., Xie, H., Feng, D., Wu, X., Song, D.Z., Roy, S., Zhao, C. (2018) Cilia-driven cerebrospinal fluid flow directs expression of urotensin neuropeptides to straighten the vertebrate body axis. Nature Genetics. 50(12):1666-1673

Djenoune, L., Desban, L., Gomez, J., Sternberg, J.R., Prendergast, A., Langui, D., Quan, F.B., Marnas, H., Auer, T.O., Rio, J.P., Del Bene, F., Bardet, P.L., Wyart, C. (2017) The dual developmental origin of spinal cerebrospinal fluid-contacting neurons gives rise to distinct functional subtypes. Scientific Reports. 7:719

England, S.J., Campbell, P.C., Banerjee, S., Swanson, A.J., Lewis, K.E. (2017) Identification and Expression Analysis of the Complete Family of Zebrafish pkd Genes.. Frontiers in cell and developmental biology. 5:5

Ribeiro, A., Monteiro, J.F., Certal, A.C., Cristovão, A.M., Saúde, L. (2017) Foxj1a is expressed in ependymal precursors, controls central canal position and is activated in new ependymal cells during regeneration in zebrafish. Open Biology. 7(11)

Böhm, U. L., Prendergast, A., Djenoune, L., Nunes Figueiredo, S., Gomez, J., Stokes, C., Kaiser, S., Suster, M., Kawakami, K., Charpentier, M., Concordet, J. P., Rio, J. P., Del Bene, F., Wyart, C. (2016) CSF-contacting neurons regulate locomotion by relaying mechanical stimuli to spinal circuits. Nature communications. 7:10866

Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549

Fidelin, K., Djenoune, L., Stokes, C., Prendergast, A., Gomez, J., Baradel, A., Del Bene, F., Wyart, C. (2015) State-Dependent Modulation of Locomotion by GABAergic Spinal Sensory Neurons. Current biology : CB. 25:3035-47

Quan, F.B., Dubessy, C., Galant, S., Kenigfest, N.B., Djenoune, L., Leprince, J., Wyart, C., Lihrmann, I., Tostivint, H. (2015) Comparative Distribution and In Vitro Activities of the Urotensin II-Related Peptides URP1 and URP2 in Zebrafish: Evidence for Their Colocalization in Spinal Cerebrospinal Fluid-Contacting Neurons. PLoS One. 10:e0119290

Djenoune, L., Khabou, H., Joubert, F., Quan, F.B., Nunes Figueiredo, S., Bodineau, L., Del Bene, F., Burcklé, C., Tostivint, H., Wyart, C. (2014) Investigation of spinal cerebrospinal fluid-contacting neurons expressing PKD2L1: evidence for a conserved system from fish to primates. Frontiers in Neuroanatomy. 8:26

Additional Citations (21):

ZFIN Staff (2023) Curation of NCBI Gene Data Via Shared Ensembl IDs (Supplemental NCBI Load). Automated Data Submission.

ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.

Zebrafish Nomenclature Committee (2022) Nomenclature Data Curation (2022). Nomenclature Committee Submission.

Zebrafish Nomenclature Committee (2021) Nomenclature Data Curation (2021). Nomenclature Committee Submission.

ZFIN Staff (2020) Addition of links from ZFIN to Expression Atlas. Semi-automated Curation.

ZFIN Staff (2017) Curation of PANTHER Gene IDs. Automated Data Submission.

ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.

Zebrafish Nomenclature Committee (2016) Nomenclature Data Curation (2016). Nomenclature Committee Submission.

Zebrafish Nomenclature Committee (2015) Nomenclature Data Curation (2015). Nomenclature Committee Submission.

Busch-Nentwich, E., Kettleborough, R., Dooley, C. M., Scahill, C., Sealy, I., White, R., Herd, C., Mehroke, S., Wali, N., Carruthers, S., Hall, A., Collins, J., Gibbons, R., Pusztai, Z., Clark, R., and Stemple, D.L. (2013) Sanger Institute Zebrafish Mutation Project mutant data submission. ZFIN Direct Data Submission.

ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.

UniProt-GOA (2011) Gene Ontology annotation based on the automatic assignment of UniProtKB Subcellular Location terms in UniProtKB/TrEMBL entries. Manually curated data.

Gaudet, P., Livstone, M.S., Lewis, S.E., Thomas, P.D. (2010) Annotation inferences using phylogenetic trees. Automated Data Submission. 12:449-62

Ensembl curators, GOA curators (2006) Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara. Manually curated data.

ZFIN Staff (2006) Curation of Ensembl Database Links. Automated Data Submission.

ZFIN Staff (2004) Temporary Manual Curation. Manually curated data.

ZFIN Staff (2003) Curation of VEGA Database Links. Automated Data Submission.

ZFIN Staff (2003) Curation of orthology data. Manually curated data.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of UniProt Keywords with GO Terms. Automated Data Submission.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission.

ZFIN Staff (2002) Curation of EMBL records. Automated Data Submission.