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Phenotype Figure Summary
Marker:
brd2a
Conditions:
Standard or Control
Publication
Data
Fish
Anatomy
Murphy
et al.
, 2017
Fig. 1
AB + MO4-brd2a
, 
AB + MO3-brd2a
brain decreased size, abnormal
fourth ventricle collapsed, abnormal
midbrain hindbrain boundary morphology, abnormal
post-vent region morphology, abnormal
Fig. 10
AB + MO3-brd2a
midbrain hindbrain boundary posterior region
en2a
expression decreased distribution, abnormal
midbrain hindbrain boundary posterior region
pax2a
expression decreased distribution, abnormal
Fig. 11
AB + MO3-brd2a
rhombomere 3
egr2b
expression decreased distribution, abnormal
Fig. 12
AB + MO3-brd2a
, 
AB + MO3-brd2a + MO4-tp53
brain apoptotic process increased occurrence, abnormal
midbrain hindbrain boundary posterior region
en2a
expression decreased distribution, abnormal
Fig. 14
AB + MO3-brd2a
hindbrain interneuron mislocalised, abnormal
hindbrain interneuron spatial pattern, abnormal
spinal cord interneuron mislocalised, abnormal
spinal cord interneuron spatial pattern, abnormal
Fig. 2
AB + MO4-brd2a
brain structure, abnormal
fourth ventricle collapsed, abnormal
midbrain hindbrain boundary morphology, abnormal
Fig. 4
AB + MO3-brd2a
brain
brd2a
expression decreased distribution, abnormal
gut
brd2a
expression decreased distribution, abnormal
pronephros
brd2a
expression decreased distribution, abnormal
retinal ganglion cell
brd2a
expression decreased distribution, abnormal
somite
brd2a
expression decreased distribution, abnormal
spinal cord neural tube
brd2a
expression decreased distribution, abnormal
whole organism
brd2a
expression decreased amount, abnormal
Fig. 5
AB + MO3-brd2a
brain apoptotic process increased occurrence, abnormal
central nervous system apoptotic process increased occurrence, abnormal
whole organism apoptotic process decreased occurrence, abnormal
Fig. 6
AB + MO3-brd2a
, 
AB + MO3-brd2a + MO4-tp53
brain cell death increased occurrence, abnormal
brain structure, abnormal
central nervous system cell death increased occurrence, abnormal
Fig. 7
AB + CRISPR1-brd2a
brain apoptotic process increased occurrence, abnormal
brain structure, abnormal
central nervous system apoptotic process increased occurrence, abnormal
Fig. S1
AB + MO3-brd2a
fourth ventricle collapsed, abnormal
mesoderm disorganized, abnormal
notochord morphology, abnormal
somite condensed, abnormal
somite irregularly shaped, abnormal
Table 1
AB + MO4-brd2a
, 
AB + MO3-brd2a + MO4-brd2a
brain structure, abnormal
Bielczyk-MaczyĆska
et al.
, 2014
Fig. S22
la2Tg + MO1-brd2a
thrombocyte decreased amount, abnormal
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