Publication	Data		Fish	Anatomy
Hoshijima et al., 2019	Fig. 3		rx3s399/s399	whole organism lacks all parts of type eye, abnormal
Muthu et al., 2016	Fig. 4		rx3w29/w29	caudal hypothalamic zone nr5a1a expression absent, abnormal caudal hypothalamic zone otpb expression absent, abnormal caudal hypothalamic zone pomca expression absent, abnormal hypothalamus fezf1 expression decreased amount, abnormal hypothalamus rx3 expression spatial pattern, abnormal hypothalamus shha expression decreased amount, abnormal hypothalamus anterior region otpb expression absent, abnormal hypothalamus dopaminergic neuron ab1-th labeling decreased amount, abnormal telencephalon fezf1 expression mislocalised, abnormal third ventricle anatomical region shha expression absent, abnormal
	Fig. 5		WT + MO1-rx3 + MO3-rx3 ,   rx3w29/w29	caudal hypothalamic zone nkx2.1 expression absent, abnormal caudal hypothalamic zone anterior region nkx2.1 expression absent, abnormal caudal hypothalamic zone anterior region pax6a expression mislocalised, abnormal hypothalamus etv4 expression increased amount, abnormal hypothalamus rx3 expression spatial pattern, abnormal hypothalamus shha expression decreased amount, abnormal hypothalamus anterior region nkx2.1 expression absent, abnormal hypothalamus anterior region nkx2.1 expression decreased amount, abnormal
	Fig. 6		WT + MO1-rx3 + MO3-rx3 ,   rx3w29/w29	hypothalamus nr5a1a expression absent, abnormal hypothalamus pomca expression absent, abnormal hypothalamus rx3 expression spatial pattern, abnormal hypothalamus shha expression decreased amount, abnormal hypothalamus ab4-h3 labeling increased amount, abnormal hypothalamus ab5-casp3 labeling increased amount, abnormal hypothalamus apoptotic process increased occurrence, abnormal hypothalamus cell population proliferation decreased occurrence, abnormal hypothalamus mitotic cell cycle process increased occurrence, abnormal
	Fig. 7		WT + MO1-rx3 + MO3-rx3	hypothalamus nkx2.1 expression spatial pattern, abnormal hypothalamus nr5a1a expression absent, abnormal hypothalamus pomca expression absent, abnormal hypothalamus ptch2 expression spatial pattern, abnormal hypothalamus rx3 expression spatial pattern, abnormal hypothalamus ab4-h3 labeling increased amount, abnormal hypothalamus mitotic cell cycle process increased occurrence, abnormal
Weger et al., 2016	Fig. 5		rx3t25327/t25327; ka404Tg	whole organism Luciferase expression increased distribution, abnormal
	Fig. S1		rx3t25327/t25327 ,   rx3t25181/t25181	adenohypophyseal placode lhx4 expression absent, abnormal adenohypophyseal placode lhx4 expression decreased amount, abnormal optic fissure pou4f4 expression absent, abnormal ventral telencephalon apoa1a expression increased distribution, abnormal
Mueller et al., 2014	Fig. 2		rx3s399/s399	cellular response to light stimulus disrupted, abnormal melanosome localization disrupted, abnormal
Cavodeassi et al., 2013	Fig. 1		rx3ne2611/ne2611; zf460Tg ,   rx3ne2611/ne2611	eye field cell fate commitment involved in camera-type eye formation disrupted, abnormal
Brown et al., 2010	Fig. 1		rx3s399/s399	optic primordium malformed, abnormal optic vesicle morphogenesis process quality, abnormal
Langenberg et al., 2008	Fig. 5		rx3s399/s399; ba2Tg	neural crest cell migration disrupted, abnormal
	Fig. 7		rx3s399/s399	ethmoid cartilage decreased size, abnormal neural crest cell migration disrupted, abnormal
Dickmeis et al., 2007	Fig. 3		rx3t25327/t25327	adenohypophysis decreased amount, abnormal adenohypophysis development disrupted, abnormal
Tessmar-Raible et al., 2007	Fig. 6		WT + MO1-rx3 + MO3-rx3 ,   rx3s399/s399 ,   rx3ne2611/ne2611	eye aplastic, abnormal
Phenotype Annotation (1994-2006)	Fig. for (ne2611)		rx3ne2611/ne2611	eye quality, abnormal forebrain quality, abnormal
	Fig. for (s399)		rx3s399/s399	eye quality, abnormal lens quality, abnormal retinal neural layer quality, abnormal retinal pigmented epithelium quality, abnormal
	Fig. for (t25181)		rx3t25181/t25181	retinal pigmented epithelium quality, abnormal sensory system quality, abnormal
	Fig. for (t25327)		rx3t25327/t25327	retinal pigmented epithelium quality, abnormal sensory system quality, abnormal
	Fig. for (w29)		rx3w29/w29 (AB)	eye quality, abnormal
Loosli et al., 2003	Fig. 1		rx3s399/s399	camera-type eye morphogenesis disrupted, abnormal eye absent, abnormal retina decreased size, abnormal
	Fig. 4		rx3s399/s399	retina development in camera-type eye disrupted, abnormal