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Phenotype Figure Summary
Marker:
cerkl
Conditions:
Standard or Control
Publication
Data
Fish
Anatomy
Yu
et al.
, 2017
Fig. 2
cerkl
hzu3/hzu3
detection of light stimulus involved in visual perception decreased process quality, abnormal
Fig. 3
cerkl
hzu3/hzu3
photoreceptor cell photoreceptor outer segment decreased length, abnormal
photoreceptor cell photoreceptor outer segment degenerate, abnormal
photoreceptor cell photoreceptor outer segment disorganized, abnormal
photoreceptor outer segment layer decreased thickness, abnormal
retinal cone cell decreased amount, abnormal
retinal outer nuclear layer decreased thickness, abnormal
retinal rod cell decreased amount, abnormal
Fig. 4
cerkl
hzu3/hzu3
retinal inner nuclear layer apoptotic process increased occurrence, abnormal
retinal photoreceptor layer apoptotic process increased occurrence, abnormal
Fig. 5
cerkl
hzu3/hzu3
retinal cone cell decreased amount, abnormal
retinal cone cell photoreceptor outer segment decreased length, abnormal
retinal cone cell photoreceptor outer segment degenerate, abnormal
retinal rod cell decreased amount, abnormal
retinal rod cell photoreceptor outer segment decreased length, abnormal
retinal rod cell photoreceptor outer segment degenerate, abnormal
retinal rod cell photoreceptor outer segment disorganized, abnormal
Fig. 6
cerkl
hzu3/hzu3
eye ab1-gnat1 labeling decreased amount, abnormal
eye ab1-grk1 labeling decreased amount, abnormal
eye Ab3-gnb1 labeling decreased amount, abnormal
eye ab5-rho labeling decreased amount, abnormal
Fig. 7
cerkl
hzu3/hzu3
eye
mertka
expression decreased amount, abnormal
eye Ab1-mertk labeling decreased amount, abnormal
retinal rod cell photoreceptor disc membrane disorganized, abnormal
retinal rod cell photoreceptor outer segment degenerate, abnormal
Fig. S3
cerkl
hzu3/hzu3
eye
gnb1b
expression increased amount, abnormal
eye
rho
expression increased amount, abnormal
Fig. S4
cerkl
hzu3/hzu3
eye photoreceptor cell photoreceptor outer segment detached from eye photoreceptor cell photoreceptor inner segment, abnormal
retina regulation of apoptotic cell clearance process quality, abnormal
retinal photoreceptor layer has extra parts of type retinal photoreceptor layer vesicle, abnormal
Fig. S5
cerkl
hzu3/hzu3
eye
ctsd
expression decreased amount, abnormal
eye
lamp1b
expression decreased amount, abnormal
eye
mertka
expression decreased amount, abnormal
Li
et al.
, 2014
Fig. 7
WT + MO3-cerkl
apoptotic process increased occurrence, abnormal
retina cell apoptotic, abnormal
Fig. 8
WT + MO3-cerkl
negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway disrupted, abnormal
Riera
et al.
, 2013
Fig. 5
WT + MO1-cerkl
eye decreased size, abnormal
head decreased size, abnormal
post-vent region shortened, abnormal
trunk curved, abnormal
Fig. 6
WT + MO1-cerkl
lens morphology, abnormal
photoreceptor outer segment layer absent, abnormal
retina layer formation disrupted, abnormal
Fig. 7
WT + MO1-cerkl
retina apoptotic, abnormal
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