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Phenotype Figure Summary
Marker:
sema3fb
Conditions:
Standard or Control
Publication
Data
Fish
Anatomy
Halabi
et al.
, 2022
Fig. 2
sema3fb
ca305/ca305
, 
sema3fb
ca306/ca306
cardiac ventricle decreased thickness, abnormal
pericardium edematous, abnormal
pericardium increased area, abnormal
Fig. 3
sema3fb
ca305/ca305
cardiac ventricle decreased volume, abnormal
heart contraction decreased rate, abnormal
Fig. 4
sema3fb
ca305/ca305
, 
sema3fb
ca306/ca306
atrium
myh6
expression decreased distribution, abnormal
atrium cardiac muscle cell ab-s46 labeling spatial pattern, abnormal
atrium decreased area, abnormal
cardiac ventricle
myh7
expression decreased distribution, abnormal
cardiac ventricle decreased length, abnormal
cardiac ventricle increased area, abnormal
heart
tnnt2a
expression decreased distribution, abnormal
heart anterior-posterior axis decreased length, abnormal
Fig. 5
sema3fb
ca305/ca305
, 
sema3fb
ca306/ca306
cardiac ventricle cardiac muscle cell decreased area, abnormal
cardiac ventricle decreased perimeter, abnormal
heart
bmp4
expression spatial pattern, abnormal
heart
tnnt2a
expression spatial pattern, abnormal
heart ab-mf20 labeling spatial pattern, abnormal
heart tube
myh6
expression spatial pattern, abnormal
heart zn-8 labeling spatial pattern, abnormal
Fig. 6
sema3fb
ca305/ca305
atrioventricular canal cardiac muscle cell
tbx2b
expression increased distribution, abnormal
atrioventricular valve asymmetrical, abnormal
endocardium
nfatc1
expression decreased distribution, abnormal
Fig. 7
sema3fb
ca305/ca305
atrium decreased area, abnormal
cardiac ventricle cardiac muscle cell decreased area, abnormal
cardiac ventricle decreased perimeter, abnormal
heart contraction decreased rate, abnormal
Weinberger
et al.
, 2020
Figure 5
ox185Tg + CRISPR5-sema3fb + CRISPR6-sema3fb
bulbus arteriosus Citrine expression increased amount, abnormal
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