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Phenotype Figure Summary
Marker:
wnt16
Conditions:
Standard or Control
Publication
Data
Fish
Anatomy
McGowan
et al.
, 2021
Fig 1
wnt16
bsl667/bsl667
, 
wnt16
bsl451/bsl451
caudal fin principal ray bone callus increased amount, abnormal
caudal fin principal ray fractured, abnormal
caudal fin principal ray mineral decreased amount, abnormal
Qu
et al.
, 2021
Figure 2
wnt16
zf3561/zf3561
(AB)
whole organism
wnt16
expression decreased amount, abnormal
Figure 3
wnt16
zf3561/zf3561
(AB)
bone tissue decreased mass density, abnormal
caudal fin absence of anatomical entity, abnormal
head bone element decreased amount, abnormal
mandibular arch skeleton deformed, abnormal
mandibular arch skeleton increased length, abnormal
mandibular arch skeleton protruding, abnormal
vertebral column curved, abnormal
vertebral column increased curvature, abnormal
vertebral column kinked, abnormal
Figure 6
wnt16
zf3561/zf3561
(AB)
whole organism
akt1
expression decreased amount, abnormal
whole organism
bnip4
expression decreased amount, abnormal
whole organism
pla2g4f.2
expression decreased amount, abnormal
whole organism
prkab1a
expression decreased amount, abnormal
whole organism
ptena
expression decreased amount, abnormal
whole organism
twsg1b
expression decreased amount, abnormal
whole organism
vegfaa
expression decreased amount, abnormal
Brunt
et al.
, 2017
Fig. 3
hu5910Tg + MO1-wnt16
, 
hu5910Tg + CRISPR1-wnt16 + CRISPR2-wnt16
Meckel's cartilage joint morphology, abnormal
palatoquadrate cartilage joint morphology, abnormal
Fig. 4
rk8Tg; sq9Tg + MO1-wnt16
embryonic skeletal joint development decreased process quality, abnormal
joint cell migration decreased occurrence, abnormal
joint cell population proliferation decreased occurrence, abnormal
Fig. 5
a131Tg; ba74Tg + MO1-wnt16
retroarticular cell population proliferation decreased occurrence, abnormal
Genthe
et al.
, 2017
Fig. S2
WT + MO2-wnt16
dorsal aorta hematopoietic stem cell
runx1
expression absent, abnormal
dorsal aorta hematopoietic stem cell absent, abnormal
somite
wnt16
expression decreased amount, abnormal
Kim
et al.
, 2014
Fig. 7
AB + MO2-wnt16
hematopoietic progenitor cell differentiation process quality, abnormal
Lee
et al.
, 2014
Fig. 4
AB + MO2-wnt16
somite
etv4
expression decreased amount, abnormal
somite
fgfr4
expression decreased amount, abnormal
ventral wall of dorsal aorta
runx1
expression decreased amount, abnormal
ventral wall of dorsal aorta hematopoietic stem cell decreased amount, abnormal
Clements
et al.
, 2011
Fig. 1
WT + MO1-wnt16 + MO2-wnt16
hematopoietic stem cell absent, abnormal
hematopoietic stem cell differentiation disrupted, abnormal
thymus T cell absent, abnormal
Fig. 2
WT + MO1-wnt16 + MO2-wnt16
intersegmental vessel spatial pattern, abnormal
trunk altered number of intersegmental vessel, abnormal
Fig. 3
WT + MO1-wnt16 + MO2-wnt16
hematopoietic stem cell differentiation disrupted, abnormal
Notch signaling pathway disrupted, abnormal
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