TALEN

TALEN1-clec14a

ID

ZDB-TALEN-191016-1

Name

TALEN1-clec14a

Previous Names

None

Target

clec14a (1)

Target Sequence 1

5' - TGTTCACTTGAACAAAAACT - 3'

Target Sequence 2

5' - TCCAGGTTTGCAATAATTCT - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Genome Build: GRCz11Chromosome: 17

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
ci15	clec14a

Expression

Gene expression in Wild Types + TALEN1-clec14a

No data available

Phenotype

Phenotype resulting from TALEN1-clec14a

No data available

Phenotype of all Fish created by or utilizing TALEN1-clec14a

Phenotype	Fish	Conditions	Figures
axial vasculature kdrl expression spatial pattern, abnormal	clec14a^ci15/ci15	standard conditions	Fig. 5 from Pociute et al., 2019
embryonic blood vessel endothelial progenitor cell cdh5 expression decreased amount, abnormal	clec14a^ci15/ci15	standard conditions	Fig. 4 from Pociute et al., 2019
intermediate cell mass of mesoderm clec14a expression decreased amount, abnormal	clec14a^ci15/ci15	standard conditions	Fig. 1 from Pociute et al., 2019
embryonic blood vessel endothelial progenitor cell kdrl expression decreased amount, abnormal	clec14a^ci15/ci15	standard conditions	Fig. 4 from Pociute et al., 2019
sprouting angiogenesis delayed, abnormal	clec14a^ci15/ci15; s843Tg	standard conditions	Fig. 2 , Fig. 4 , Fig. 5 from Pociute et al., 2019
intersegmental vessel angiogenic sprout decreased length, abnormal	clec14a^ci15/ci15; s843Tg	standard conditions	Fig. 2 , Fig. 5 from Pociute et al., 2019
parachordal vessel incomplete structure, abnormal	clec14a^ci15/ci15; s843Tg	standard conditions	Fig. 2 from Pociute et al., 2019
intersegmental vessel decreased amount, abnormal	clec14a^ci15/ci15; s843Tg	standard conditions	Fig. 5 from Pociute et al., 2019
dorsal longitudinal anastomotic vessel immature, abnormal	clec14a^ci15/ci15; s843Tg	standard conditions	Fig. 2 from Pociute et al., 2019
intersegmental vessel cldn5b expression spatial pattern, abnormal	clec14a^ci15/ci15 + MO1-cd93	standard conditions	Fig. 3 from Pociute et al., 2019
intersegmental vessel kdrl expression decreased amount, abnormal	clec14a^ci15/ci15 + MO1-cd93	standard conditions	Fig. 3 from Pociute et al., 2019
intersegmental vessel fli1 expression decreased amount, abnormal	clec14a^ci15/ci15 + MO1-cd93	standard conditions	Fig. 3 from Pociute et al., 2019
intersegmental vessel cdh5 expression spatial pattern, abnormal	clec14a^ci15/ci15 + MO1-cd93	standard conditions	Fig. 3 from Pociute et al., 2019
intersegmental vessel cldn5b expression decreased amount, abnormal	clec14a^ci15/ci15 + MO1-cd93	standard conditions	Fig. 3 from Pociute et al., 2019
intersegmental vessel kdrl expression spatial pattern, abnormal	clec14a^ci15/ci15 + MO1-cd93	standard conditions	Fig. 3 from Pociute et al., 2019
intersegmental vessel fli1 expression spatial pattern, abnormal	clec14a^ci15/ci15 + MO1-cd93	standard conditions	Fig. 3 from Pociute et al., 2019
intersegmental vessel cdh5 expression decreased amount, abnormal	clec14a^ci15/ci15 + MO1-cd93	standard conditions	Fig. 3 from Pociute et al., 2019
axial vasculature kdrl expression spatial pattern, abnormal	clec14a^ci15/ci15 + MO1-vegfaa	standard conditions	Fig. 5 from Pociute et al., 2019
embryonic blood vessel endothelial progenitor cell kdrl expression decreased amount, abnormal	clec14a^ci15/ci15 + MO2-etsrp	standard conditions	Fig. 4 from Pociute et al., 2019
embryonic blood vessel endothelial progenitor cell kdrl expression decreased distribution, abnormal	clec14a^ci15/ci15 + MO2-etsrp	standard conditions	Fig. 4 from Pociute et al., 2019
embryonic blood vessel endothelial progenitor cell cdh5 expression decreased amount, abnormal	clec14a^ci15/ci15 + MO2-etsrp	standard conditions	Fig. 4 from Pociute et al., 2019
embryonic blood vessel endothelial progenitor cell cdh5 expression decreased distribution, abnormal	clec14a^ci15/ci15 + MO2-etsrp	standard conditions	Fig. 4 from Pociute et al., 2019
sprouting angiogenesis delayed, abnormal	clec14a^ci15/ci15; s843Tg + MO1-cd93	standard conditions	Fig. 2 from Pociute et al., 2019
sprouting angiogenesis delayed, exacerbated	clec14a^ci15/ci15; s843Tg + MO1-cd93	standard conditions	Fig. 2 from Pociute et al., 2019
parachordal vessel incomplete structure, exacerbated	clec14a^ci15/ci15; s843Tg + MO1-cd93	standard conditions	Fig. 2 from Pociute et al., 2019
angiogenic sprout mislocalised, abnormal	clec14a^ci15/ci15; s843Tg + MO1-cd93	standard conditions	Fig. 2 from Pociute et al., 2019
intersegmental vessel angiogenic sprout decreased length, exacerbated	clec14a^ci15/ci15; s843Tg + MO1-cd93	standard conditions	Fig. 2 from Pociute et al., 2019
intersegmental vessel angiogenic sprout decreased length, abnormal	clec14a^ci15/ci15; s843Tg + MO1-cd93	standard conditions	Fig. 2 from Pociute et al., 2019
dorsal longitudinal anastomotic vessel immature, exacerbated	clec14a^ci15/ci15; s843Tg + MO1-cd93	standard conditions	Fig. 2 from Pociute et al., 2019
intersegmental vessel decreased length, abnormal	clec14a^ci15/ci15; s843Tg + MO1-vegfaa	standard conditions	Fig. 5 from Pociute et al., 2019
intersegmental vessel decreased amount, exacerbated	clec14a^ci15/ci15; s843Tg + MO1-vegfaa	standard conditions	Fig. 5 from Pociute et al., 2019
dorsal longitudinal anastomotic vessel immature, abnormal	clec14a^ci15/ci15; s843Tg + MO1-vegfaa	standard conditions	Fig. 5 from Pociute et al., 2019
sprouting angiogenesis delayed, exacerbated	clec14a^ci15/ci15; s843Tg + MO1-vegfaa	standard conditions	Fig. 5 from Pociute et al., 2019
parachordal vessel incomplete structure, exacerbated	clec14a^ci15/ci15; s843Tg + MO1-vegfaa	standard conditions	Fig. 5 from Pociute et al., 2019
intersegmental vessel angiogenic sprout decreased length, exacerbated	clec14a^ci15/ci15; s843Tg + MO1-vegfaa	standard conditions	Fig. 5 from Pociute et al., 2019
sprouting angiogenesis delayed, exacerbated	clec14a^ci15/ci15; s843Tg + MO2-etsrp	standard conditions	Fig. 4 from Pociute et al., 2019
intersegmental vessel angiogenic sprout decreased length, exacerbated	clec14a^ci15/ci15; s843Tg + MO2-etsrp	standard conditions	Fig. 4 from Pociute et al., 2019
angiogenic sprout mislocalised, exacerbated	clec14a^ci15/ci15; s843Tg + MO2-etsrp	standard conditions	Fig. 4 from Pociute et al., 2019

Citations

Include unpublished citations

Pociute, K., Schumacher, J.A., Sumanas, S. (2019) Clec14a genetically interacts with Etv2 and Vegf signaling during vasculogenesis and angiogenesis in zebrafish. BMC Developmental Biology. 19:6

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