ZFIN ID: ZDB-TALEN-180411-1
TALEN Name: TALEN2-vegfaa
Target: vegfaa (1)
Source:
Target Sequence 1:
5' - TATTTGATACAGTTAT - 3'
   
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Target Sequence 2:
5' - ACAGCAGACAGATGGAG - 3'
   
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  (Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.)
TARGET LOCATIONS
No data available
CONSTRUCTS WITH SEQUENCES FROM TALEN2-vegfaa No data available
GENOMIC FEATURES CREATED WITH TALEN2-vegfaa
Genomic Feature Affected Genomic Regions    
zf1090 vegfaa    
zf1091 vegfaa    
GENE EXPRESSION
Gene expression in Wild Types + TALEN2-vegfaa No data available
PHENOTYPE
Phenotype resulting from TALEN2-vegfaa
No data available

Phenotype of all Fish created by or utilizing TALEN2-vegfaa
Phenotype Fish Conditions Figures
whole organism anterior-posterior axis decreased length, abnormal vegfaazf1090/zf1090(AB) standard conditions Fig. 1 from Jin et al., 2017
heart structure, abnormal vegfaazf1090/zf1090 control Fig. 4 with image from Zhu et al., 2017
ventricular myocardium bmp4 expression mislocalised, abnormal vegfaazf1090/zf1090 control Fig. 4 with image from Zhu et al., 2017
axial blood vessel efnb2a expression absent, abnormal vegfaazf1090/zf1090(AB) standard conditions Fig. 2 from Jin et al., 2017
heart increased length, abnormal vegfaazf1090/zf1090 control Fig. 4 with image from Zhu et al., 2017
axial blood vessel hey2 expression absent, abnormal vegfaazf1090/zf1090(AB) standard conditions Fig. 2 from Jin et al., 2017
axial blood vessel dab2 expression increased distribution, abnormal vegfaazf1090/zf1090(AB) standard conditions Fig. 2 from Jin et al., 2017
pericardium edematous, abnormal vegfaazf1090/zf1090(AB) standard conditions Fig. 1 from Jin et al., 2017
heart linear, abnormal vegfaazf1090/zf1090 control Fig. 4 with image from Zhu et al., 2017
cardioblast migration to the midline involved in heart field formation delayed, abnormal vegfaazf1090/zf1090 control Fig. 3 with image from Zhu et al., 2017
heart decreased width, abnormal vegfaazf1090/zf1090 control Fig. 4 with image from Zhu et al., 2017
heart hypotrophic, abnormal vegfaazf1090/zf1090 control Fig. 4 with image from Zhu et al., 2017
presumptive cardiac ventricle primitive heart tube cardioblast migration to the midline involved in heart field formation delayed, abnormal vegfaazf1090/zf1090 control Fig. 3 with image from Zhu et al., 2017
heart looping process quality, abnormal vegfaazf1090/zf1090 control Fig. 4 with image from Zhu et al., 2017
blood circulation disrupted, abnormal vegfaazf1090/zf1090(AB) standard conditions Fig. 1 from Jin et al., 2017
heart tube formation decreased occurrence, abnormal la116Tg ; sd7Tg ; vegfaazf1090/zf1090 control Fig. 1 with image from Zhu et al., 2017
cardiac ventricle hypotrophic, abnormal la116Tg ; sd7Tg ; vegfaazf1090/zf1090 control Fig. 1 with image from Zhu et al., 2017
heart linear, abnormal la116Tg ; sd7Tg ; vegfaazf1090/zf1090 control Fig. 1 with image from Zhu et al., 2017
heart valve malformed, abnormal la116Tg ; sd7Tg ; vegfaazf1090/zf1090 control Fig. 1 with image from Zhu et al., 2017
endocardium endothelial cell accumulation heart anatomical space, abnormal la116Tg ; sd7Tg ; vegfaazf1090/zf1090 control Fig. 1 with image from Zhu et al., 2017
heart structure, abnormal la116Tg ; sd7Tg ; vegfaazf1090/zf1090 control Fig. 1 with image from Zhu et al., 2017
heart looping process quality, abnormal la116Tg ; sd7Tg ; vegfaazf1090/zf1090 control Fig. 1 with image from Zhu et al., 2017
atrium hypotrophic, abnormal la116Tg ; sd7Tg ; vegfaazf1090/zf1090 control Fig. 1 with image from Zhu et al., 2017
dorsal longitudinal anastomotic vessel absent, abnormal s843Tg ; vegfaazf1090/zf1090 standard conditions Fig. 2 from Jin et al., 2017
posterior cardinal vein blood vessel endothelial cell increased amount, abnormal s843Tg ; vegfaazf1090/zf1090 standard conditions Fig. 3 from Jin et al., 2017
dorsal aorta blood vessel endothelial cell absent, abnormal s843Tg ; vegfaazf1090/zf1090 standard conditions Fig. 3 from Jin et al., 2017
dorsal aorta absent, abnormal s843Tg ; vegfaazf1090/zf1090 standard conditions Fig. 2 from Jin et al., 2017
intersegmental vessel angiogenic sprout decreased length, abnormal s843Tg ; vegfaazf1090/zf1090 standard conditions Fig. 4 from Jin et al., 2017
cerebellar central artery angiogenic sprout decreased amount, abnormal s843Tg ; vegfaazf1090/zf1090 standard conditions Fig. 5 from Jin et al., 2017
metencephalic artery absent, abnormal s843Tg ; vegfaazf1090/zf1090 standard conditions Fig. 6 from Jin et al., 2017
mesencephalic vein absent, abnormal s843Tg ; vegfaazf1090/zf1090 standard conditions Fig. 6 from Jin et al., 2017
intersegmental vessel angiogenic sprout decreased amount, abnormal s843Tg ; vegfaazf1090/zf1090 standard conditions Fig. 4 from Jin et al., 2017
cerebellar central artery decreased amount, abnormal s843Tg ; vegfaazf1090/zf1090 standard conditions Fig. 5 from Jin et al., 2017
mesencephalic artery absent, abnormal s843Tg ; vegfaazf1090/zf1090 standard conditions Fig. 5Fig. 6 from Jin et al., 2017
cerebellar central artery angiogenic sprout decreased amount, abnormal s843Tg ; vegfaazf1091/zf1091 standard conditions Fig. 5 from Jin et al., 2017
mesencephalic artery absent, abnormal s843Tg ; vegfaazf1091/zf1091 standard conditions Fig. 5 from Jin et al., 2017
cerebellar central artery decreased amount, abnormal s843Tg ; vegfaazf1091/zf1091 standard conditions Fig. 5 from Jin et al., 2017
heart cardiac muscle cell decreased amount, abnormal vegfaazf1090/zf1090 ; f2Tg control Fig. 5 with image from Zhu et al., 2017
cardiac ventricle cardiac muscle cell decreased amount, abnormal vegfaazf1090/zf1090 ; f2Tg control Fig. 5 with image from Zhu et al., 2017
Genome Resources:
CITATIONS (2)