ZFIN ID: ZDB-MRPHLNO-111207-3
Morpholino Name: MO2-def6a
Target: def6a (1)
Previous Name: def6 splice MO (1)

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Sequence:
5' - AAAGAGAGCATACCTTGTCCAGGAT - 3'
   
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  (Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.)
Note: Splice-blocking MO (exon2/intron2 boundary).
TARGET LOCATION
No data available
CONSTRUCTS WITH SEQUENCES FROM MO2-def6a No data available
GENE EXPRESSION
Gene expression in Wild Types + MO2-def6a
Expressed Gene Anatomy Figures
bmp2b Fig. 4 with image from Goudevenou et al., 2011
bmp4 Fig. 4 with image from Goudevenou et al., 2011
cdx4 Fig. 4 with image from Goudevenou et al., 2011
chrd Fig. 4 with image from Goudevenou et al., 2011
ctslb Fig. 5 with image from Goudevenou et al., 2011
dlx3b Fig. 5 with image from Goudevenou et al., 2011
egr2b Fig. 4 with image from Goudevenou et al., 2011
gsc Fig. 4 with image from Goudevenou et al., 2011
myod1 Fig. 5 with image from Goudevenou et al., 2011
pax2a Fig. 4 with image from Goudevenou et al., 2011
tbxta Fig. 4 with imageFig. 5 with image from Goudevenou et al., 2011
PHENOTYPE
Phenotype resulting from MO2-def6a
Phenotype Figures
axis decreased length, abnormal Fig. 2 with imageFig. 3 with imageFig. 6 with imageFig. 9 with imageFig. S2 with image from Goudevenou et al., 2011
axis elongation disrupted, abnormal Fig. 2 with image from Goudevenou et al., 2011
brain morphology, abnormal Fig. 6 with imageFig. 9 with imageFig. S2 with image from Goudevenou et al., 2011
cell migration involved in gastrulation disrupted, abnormal Fig. 2 with imageFig. 6 with imageFig. 9 with image from Goudevenou et al., 2011
cell migration involved in mesendoderm migration disrupted, abnormal Fig. 4 with image from Goudevenou et al., 2011
ceratohyal cartilage mislocalised posteriorly, abnormal Fig. 7 with image from Goudevenou et al., 2011
convergent extension involved in axis elongation disrupted, abnormal Fig. 5 with image from Goudevenou et al., 2011
convergent extension involved in gastrulation disrupted, abnormal Fig. 5 with image from Goudevenou et al., 2011
convergent extension involved in neural plate elongation disrupted, abnormal Fig. 5 with image from Goudevenou et al., 2011
eye decreased distance eye, abnormal Fig. 9 with image from Goudevenou et al., 2011
eye increased distance eye, abnormal Fig. 7 with image from Goudevenou et al., 2011
forebrain structure, abnormal Fig. 9 with image from Goudevenou et al., 2011
head anterior region flattened, abnormal Fig. 7 with image from Goudevenou et al., 2011
hindbrain neural keel increased width, abnormal Fig. 4 with image from Goudevenou et al., 2011
Meckel's cartilage decreased length, abnormal Fig. 7 with image from Goudevenou et al., 2011
Meckel's cartilage shape, abnormal Fig. 7 with image from Goudevenou et al., 2011
midbrain hindbrain boundary neural keel increased width, abnormal Fig. 4 with image from Goudevenou et al., 2011
neural plate increased width, abnormal Fig. 5 with image from Goudevenou et al., 2011
notochord decreased length, abnormal Fig. 5 with image from Goudevenou et al., 2011
notochord increased width, abnormal Fig. 5 with image from Goudevenou et al., 2011
notochord undulate, abnormal Fig. 5 with imageFig. S2 with image from Goudevenou et al., 2011
paraxial mesoderm adaxial cell increased distance paraxial mesoderm adaxial cell, abnormal Fig. 5 with image from Goudevenou et al., 2011
paraxial mesoderm formation disrupted, abnormal Fig. 5 with image from Goudevenou et al., 2011
pericardium edematous, abnormal Fig. S2 with image from Goudevenou et al., 2011
polster mislocalised posteriorly, abnormal Fig. 5 with image from Goudevenou et al., 2011
segmental plate curved, abnormal Fig. 5 with image from Goudevenou et al., 2011
segmental plate increased width, abnormal Fig. 5 with image from Goudevenou et al., 2011
somite morphology, abnormal Fig. 5 with imageFig. 6 with imageFig. S2 with image from Goudevenou et al., 2011
tail bud truncated, abnormal Fig. 6 with imageFig. S2 with image from Goudevenou et al., 2011
whole organism anterior-posterior axis decreased length, abnormal Fig. 2 with imageFig. 6 with imageFig. S2 with image from Goudevenou et al., 2011

Phenotype of all Fish created by or utilizing MO2-def6a
Phenotype Fish Conditions Figures
whole organism anterior-posterior axis decreased length, abnormal WT + MO2-def6a standard conditions Fig. 2 with imageFig. 6 with imageFig. S2 with image from Goudevenou et al., 2011
paraxial mesoderm formation disrupted, abnormal WT + MO2-def6a standard conditions Fig. 5 with image from Goudevenou et al., 2011
convergent extension involved in axis elongation disrupted, abnormal WT + MO2-def6a standard conditions Fig. 5 with image from Goudevenou et al., 2011
convergent extension involved in gastrulation disrupted, abnormal WT + MO2-def6a standard conditions Fig. 5 with image from Goudevenou et al., 2011
cell migration involved in gastrulation disrupted, abnormal WT + MO2-def6a standard conditions Fig. 2 with imageFig. 6 with imageFig. 9 with image from Goudevenou et al., 2011
neural plate increased width, abnormal WT + MO2-def6a standard conditions Fig. 5 with image from Goudevenou et al., 2011
segmental plate curved, abnormal WT + MO2-def6a standard conditions Fig. 5 with image from Goudevenou et al., 2011
segmental plate increased width, abnormal WT + MO2-def6a standard conditions Fig. 5 with image from Goudevenou et al., 2011
eye decreased distance eye, abnormal WT + MO2-def6a standard conditions Fig. 9 with image from Goudevenou et al., 2011
hindbrain neural keel increased width, abnormal WT + MO2-def6a standard conditions Fig. 4 with image from Goudevenou et al., 2011
axis decreased length, abnormal WT + MO2-def6a standard conditions Fig. 2 with imageFig. 3 with imageFig. 6 with imageFig. 9 with imageFig. S2 with image from Goudevenou et al., 2011
axis elongation disrupted, abnormal WT + MO2-def6a standard conditions Fig. 2 with image from Goudevenou et al., 2011
Meckel's cartilage shape, abnormal WT + MO2-def6a standard conditions Fig. 7 with image from Goudevenou et al., 2011
eye increased distance eye, abnormal WT + MO2-def6a standard conditions Fig. 7 with image from Goudevenou et al., 2011
forebrain structure, abnormal WT + MO2-def6a standard conditions Fig. 9 with image from Goudevenou et al., 2011
polster mislocalised posteriorly, abnormal WT + MO2-def6a standard conditions Fig. 5 with image from Goudevenou et al., 2011
cell migration involved in mesendoderm migration disrupted, abnormal WT + MO2-def6a standard conditions Fig. 4 with image from Goudevenou et al., 2011
brain morphology, abnormal WT + MO2-def6a standard conditions Fig. 6 with imageFig. 9 with imageFig. S2 with image from Goudevenou et al., 2011
midbrain hindbrain boundary neural keel increased width, abnormal WT + MO2-def6a standard conditions Fig. 4 with image from Goudevenou et al., 2011
paraxial mesoderm adaxial cell increased distance paraxial mesoderm adaxial cell, abnormal WT + MO2-def6a standard conditions Fig. 5 with image from Goudevenou et al., 2011
somite morphology, abnormal WT + MO2-def6a standard conditions Fig. 5 with imageFig. 6 with imageFig. S2 with image from Goudevenou et al., 2011
tail bud truncated, abnormal WT + MO2-def6a standard conditions Fig. 6 with imageFig. S2 with image from Goudevenou et al., 2011
notochord decreased length, abnormal WT + MO2-def6a standard conditions Fig. 5 with image from Goudevenou et al., 2011
Meckel's cartilage decreased length, abnormal WT + MO2-def6a standard conditions Fig. 7 with image from Goudevenou et al., 2011
convergent extension involved in neural plate elongation disrupted, abnormal WT + MO2-def6a standard conditions Fig. 5 with image from Goudevenou et al., 2011
notochord increased width, abnormal WT + MO2-def6a standard conditions Fig. 5 with image from Goudevenou et al., 2011
ceratohyal cartilage mislocalised posteriorly, abnormal WT + MO2-def6a standard conditions Fig. 7 with image from Goudevenou et al., 2011
head anterior region flattened, abnormal WT + MO2-def6a standard conditions Fig. 7 with image from Goudevenou et al., 2011
pericardium edematous, abnormal WT + MO2-def6a standard conditions Fig. S2 with image from Goudevenou et al., 2011
notochord undulate, abnormal WT + MO2-def6a standard conditions Fig. 5 with imageFig. S2 with image from Goudevenou et al., 2011
axis decreased length, abnormal WT + MO1-wnt11 + MO2-def6a standard conditions Fig. 9 with image from Goudevenou et al., 2011
cell migration involved in gastrulation disrupted, abnormal WT + MO1-wnt11 + MO2-def6a standard conditions Fig. 9 with image from Goudevenou et al., 2011
forebrain anterior region aplastic, abnormal WT + MO1-wnt11 + MO2-def6a standard conditions Fig. 9 with image from Goudevenou et al., 2011
eye fused with eye, abnormal WT + MO1-wnt11 + MO2-def6a standard conditions Fig. 9 with image from Goudevenou et al., 2011
Genome Resources:
CITATIONS (1)