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Figure 6

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Xu et al., 2022 - Wnt/β-Catenin Signaling Pathway Is Strongly Implicated in Cadmium-Induced Developmental Neurotoxicity and Neuroinflammation: Clues from Zebrafish Neurobehavior and In Vivo Neuroimaging

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Figure 6

Role of zebrafish Wnt signaling pathway in Cd²⁺-induced microgliosis and neuroinflammation. (A–D) Morphological alterations of microglia in 6 dpf Tg(ApoE-EGFP) zebrafish larvae, and quantification of morphological parameters. (E,F) In vivo neuroimaging and microglia counting in the optic tectum region of 6 dpf zebrafish larvae. (G) Expression patterns of genes closely related with microgliosis and neuroinflammatory response. The numerical values are presented as either mean ± SEM in histograms, or median and mean, while whiskers show 90% confidence levels in boxplots. The results of either nonparametric test or ANOVA followed by multiple comparison test are listed in Table S2. “*” indicates significant differences (* p < 0.05, ** p < 0.01, *** p < 0.001).

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This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Int. J. Mol. Sci.