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ZDB-IMAGE-200730-7

Genes

Publication

Lee et al., 2020 - Mutations in FAM50A suggest that Armfield XLID syndrome is a spliceosomopathy

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Figures for Lee et al., 2020

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Fig. 5 Major spliceosome effectors are upregulated in <italic>fam50a</italic> KO zebrafish.

Representative lateral images of whole-mount in situ hybridization performed on 3 day post-fertilization larvae validate RNA-seq data (Table 2) from fam50a KO (homozygous mutant) vs wild-type (WT). Number of embryos assessed with similar results: prpf3, n = 11; prpf4, n = 10; prpf6, n = 11; prpf8, n = 10; prpf31, n = 11; eftud2, n = 10; snrnp200, n = 11; sf3b4, n = 11; snrpe, n = 11; eif4a3, n = 9; snapc4, n = 11; ice1, n = 10. Scale bars; 200 μm.

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Acknowledgments

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