ZFIN Image: Hsieh et al., 2018, Fig. 2

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Figure Caption

Fig. 2 Ppar? deficiency did not affect the formation of neural progenitors. A: GW6471 treatment or injection of pparaa ?LBD or pparab ?LBD reduced the expression of acox1, as examined by quantitative real?time polymerase chain reaction (RT?qPCR). B: Schematic of pparaa ?LBD and pparab ?LBD deletion constructs. DBD, DNA?binding domain; LBD, ligand?binding domain. C?J: GW6471 treatment (C,D), injection of pparaa ?LBD or pparab ?LBD, and coinjection of pparaa ?LBD and pparab ?LBD (E,F) did not alter the expression of neural progenitor marker sox2 and the anterior neural plate marker otx2b, as examined using whole?mount in situ hybridization (C,E,G,I) and quantified through RT?qPCR (D,F,H,J). Note that the expression of sox2 at 72 hpf was not affected by Ppar? deficiency (G?J). The data represent three independent experiments. Values are expressed as the mean?�?standard deviation. **P?

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Acknowledgments

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