Gene

acox1

ID
ZDB-GENE-041010-219
Name
acyl-CoA oxidase 1, palmitoyl
Symbol
acox1 Nomenclature History
Previous Names
  • wu:fb59h12
  • zgc:114033
  • zgc:92584
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to have fatty acid binding activity; flavin adenine dinucleotide binding activity; and palmitoyl-CoA oxidase activity. Predicted to be involved in fatty acid beta-oxidation using acyl-CoA oxidase; lipid homeostasis; and very long-chain fatty acid metabolic process. Predicted to localize to peroxisome. Is expressed in several structures, including female organism; heart; immature eye; liver; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in peroxisomal acyl-CoA oxidase deficiency. Orthologous to human ACOX1 (acyl-CoA oxidase 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
14 figures from 11 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With acox1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
peroxisomal acyl-CoA oxidase deficiency Alliance Peroxisomal acyl-CoA oxidase deficiency 264470
Mitchell syndrome 618960
Associated With acox1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR002655 Acyl-CoA oxidase, C-terminal
Domain IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain
Domain IPR029320 Acyl-coenzyme A oxidase, N-terminal
Family IPR012258 Acyl-CoA oxidase
Family IPR034171 Peroxisomal acyl-coenzyme A oxidase
Homologous_superfamily IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily
Homologous_superfamily IPR036250 Acyl-CoA dehydrogenase-like, C-terminal
Homologous_superfamily IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily
Domain Details Per Protein
Protein Length Acyl-CoA dehydrogenase-like, C-terminal Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily Acyl-CoA oxidase Acyl-CoA oxidase, C-terminal Acyl-CoA oxidase/dehydrogenase, central domain Acyl-coenzyme A oxidase, N-terminal Peroxisomal acyl-coenzyme A oxidase
UniProtKB:Q5XIZ4 660
UniProtKB:F1R071 660
UniProtKB:F1R3V9 660
UniProtKB:Q4QRE2 660
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations