ZFIN Image: Venero Galanternik M. et al., 2016, Fig. 6

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Figure Caption

Fig. 6

glypican4^fr6 mutants show reduced expression levels of patched2, engrailed1a and engrailed2a. (A–D) 10× lateral views of the expression of the Hh target patched2 in sibling and glypican4^fr6 mutant embryos at 24 and 30 hpf. (E-H) 10× lateral views of the expression of the Hh target engrailed1a in sibling and glypican4^fr6 mutant embryos at 24 and 30 hpf. (I-L) 10x lateral views of the expression of the Hh target engrailed2a in sibling and glypican4^fr6 mutant embryos at 24 and 30 hpf. These Hh targets show a drastic, increasing downregulation in glypican4^fr6 mutants over time compared to their siblings. (M-N) 10× lateral views of the expression of the Bmp target id1 in sibling and glypican4^fr6 mutant embryos at 24 hpf. This Bmp target shows a drastic upregulation in glypican4^fr6 mutants compared to their siblings.

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Acknowledgments

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Reprinted from Developmental Biology, 419(2), Venero Galanternik M., Lush, M.E., Piotrowski, T., Glypican4 Modulates Lateral Line Collective Cell Migration Non Cell-Autonomously, 321-335, Copyright (2016) with permission from Elsevier. Full text @ Dev. Biol.