ZFIN Image: Sisson et al., 2015, Fig. 3

Image

Figure Caption

Fig. 3

Cranial neural crest cell migration and specification is unaffected in gpc4 and wnt5b mutants. (A?O) Neural crest specification appears normal within gpc4 and wnt5b mutants Scale bar = 100 �m. (A?I) Pre-migratory neural crest markers. 6 somites. (J?O)Pharyngeal arch markers. (J?L) 28 hpf. (M?O) 32 hpf. (P?R) Migration of neural crest appears to be unaffected in gpc4 and wnt5b mutants when compared to wild type fish. Tg(fli1a:EGFP)^y1 embryos have neural crest derived cells labeled by GFP expression. Embryos were fixed at 33 hpf and stained with the Alcama (Zn5) antibody (red). Pharyngeal arches are numbered. Scale bar = 50 �m.

Figure Data

Expression / Labeling details

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Mechanisms of Development, 138 Pt 3, Sisson, B.E., Dale, R.M., Mui, S.R., Topczewska, J.M., Topczewski, J., A role of glypican4 and wnt5b in chondrocyte stacking underlying craniofacial cartilage morphogenesis, 279-90, Copyright (2015) with permission from Elsevier. Full text @ Mech. Dev.