ZFIN Image: McGraw et al., 2014, Fig. 4

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Figure Caption

Fig. 4

Wnt activity is prematurely and progressively decreased in krm1^nl10 mutants. (A-R) Expression of the Wnt targets, lef1, axin2 and sef, in the pLLP at 32, 36 and 40hpf in WT and krm1^nl10 embryos. In WT primordia, expression domains of lef1 (A,C,E), axin2 (G,I,K) and sef (M,O,Q) are progressively decreased between 32 and 40hpf. In krm1^nl10 mutant primordia, Wnt target expression is similar to WT at 32hpf (B,H,N). At 36hpf, expression domains are decreased in mutants compared with WT (D,J,P), and are absent in mutants at 40hpf (F,L,R). dusp6 is expressed in the leading and mid-zones of WT primordia between 32 and 40hpf (S,U,W); expression is absent in the leading zone of krm1^nl10 mutant primordia at these stages (T,V,X). Scale bars: 20 μm.

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Expression / Labeling details

Acknowledgments

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