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Fig. 4

ID
ZDB-IMAGE-120601-61
Genes
Source
Figures for van der Velden et al., 2012
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Figure Caption

Fig. 4 LPM patterning and the RA-signaling response in ring1b mutants. (A-L) Double in situ hybridization for nkx2.5 in red and tbx5 (A-D), dhrs3 (E-H) and hoxb5b (I-L) in blue at 10 ss and 15 ss shows similar staining patterns in wild-type and ring1b mutants. Arrowheads indicate staining at the pectoral fin mesenchyme. (M-X) Dorsal views of embryos stained for the RA targets dhrs3 (M-P), hoxb5b (Q-T) and meis3 (U-X) at 20 ss and 32 hpf. Expression of hoxb5b and meis3 is normal in the ring1b LPM at 20 ss and 32 hpf, whereas dhrs3 expression is upregulated in the ring1b LPM at 32 hpf (P). Arrowheads indicate staining at the fin bud region.

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