ZFIN Image: Zhu et al., 2012, Fig. 5

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Figure Caption

Fig. 5

Expression of Early Sympathoadrenal Markers Is Absent in MYCN Transgenic Embryos during Early Development (A and B) Top panels: DβH; lower panels: MYCN transgenic fish. Expression of sympathoadrenal cell markers at 54 hpf (A) and 80 hpf (B). The magnified view of the boxed region is shown on the right. Arrows point to the superior cervical ganglion. Scale bars represent 50 μm (left panels) and 100 μm (right panels, magnified view). (C) Diagram of the genetic interactions of sympathoadrenal genes during early development. Arrows indicate the activation of target genes. Curved arrows indicate positive feedback regulation. See also Figure S5.

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Expression / Labeling details

Acknowledgments

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Reprinted from Cancer Cell, 21(3), Zhu, S., Lee, J.S., Guo, F., Shin, J., Perez-Atayde, A.R., Kutok, J.L., Rodig, S.J., Neuberg, D.S., Helman, D., Feng, H., Stewart, R.A., Wang, W., George, R.E., Kanki, J.P., and Look, A.T., Activated ALK Collaborates with MYCN in Neuroblastoma Pathogenesis, 362-373, Copyright (2012) with permission from Elsevier. Full text @ Cancer Cell