Gene

tfap2a

ID
ZDB-GENE-011212-6
Name
transcription factor AP-2 alpha
Symbol
tfap2a Nomenclature History
Previous Names
  • ap2 (1)
  • ap2a (1)
  • cb93 (1)
  • fb83f04
  • fc31a07 (1)
  • lockjaw
  • low
  • mob (1)
  • mont blanc (1)
  • wu:fb83f04 (1)
  • wu:fc31a07 (1)
Type
protein_coding_gene
Location
Chr: 24 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including animal organ development; iridophore differentiation; and nervous system development. Localizes to nucleus. Is expressed in several structures, including ectoderm; nervous system; neural crest; neural tube; and pronephros. Human ortholog(s) of this gene implicated in branchiooculofacial syndrome. Orthologous to human TFAP2A (transcription factor AP-2 alpha).
Genome Resources
Note
None
Expression
All Expression Data
71 figures from 49 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
37 figures from 14 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tfap2a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
branchiooculofacial syndrome Alliance Branchiooculofacial syndrome 113620
Associated With tfap2a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR008121 Transcription factor AP-2 alpha, N-terminal
Domain IPR013854 Transcription factor AP-2, C-terminal
Family IPR004979 Transcription factor AP-2
Domain Details Per Protein
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-tfap2a polyclonal IgG Rabbit
  • IHC
AnaSpec
2
Ab2-tfap2a polyclonal Goat
  • IHC
LifeSpan BioSciences, Inc.
3
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations