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Fig. 5
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Fig. 5 Molecular defects in neural crest specification in sym1 mutants. Dorsal views of wild-type (A–E) and sym1 mutant (F–J) embryos. Neural plate border expression of foxd3 (A, F), tfap2a (B, G), snai1b (C, H), sox10 (D, I) and ctn (ctn E, J) in 3-somite-stage embryos. Decreased expression of sox10, snai1b and ctn, but not foxd3 and tfap2a is evident in sym1 mutants. Arrows indicate position of midbrain–hindbrain boundary.
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Reprinted from Developmental Biology, 292(1), Stewart, R.A., Arduini, B.L., Berghmans, S., George, R.E., Kanki, J.P., Henion, P.D., and Look, A.T., Zebrafish foxd3 is selectively required for neural crest specification, migration and survival, 174-188, Copyright (2006) with permission from Elsevier. Full text @ Dev. Biol.