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Fig. 1 Effects of RA on rod and cone opsin expression. Panels show lateral views of whole-mounted eyes from DMSO-treated zebrafish embryos (A, C, E, G) or embryos treated with RA (B, D, F, H) at 51 hpf and fixed at 75 hpf. Embryos were hybridized with rod opsin riboprobes (A and B), red cone opsin riboprobes (C and D), blue cone opsin riboprobes (E and F), or UV cone opsin riboprobes (G and H). v, ventral (for all panels); scale bar = 40 μm; * indicates slight damage to eye tissue during processing.
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Reprinted from Developmental Biology, 287(1), Prabhudesai, S.N., Cameron, D.A., and Stenkamp, D.L., Targeted effects of retinoic acid signaling upon photoreceptor development in zebrafish, 157-167, Copyright (2005) with permission from Elsevier. Full text @ Dev. Biol.