cxxc1b

ID

ZDB-GENE-030728-4

Name

CXXC finger protein 1b

Symbol

cxxc1b Nomenclature History

Previous Names

cfp1 (1)
cxxc1
LWS-2 (1)
opn1lw2 (1)
zgc:55527

Type

protein_coding_gene

Location

Chr: 11 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable methylated histone binding activity. Acts upstream of or within blood vessel development; epigenetic regulation of gene expression; and hemopoiesis. Predicted to be located in nucleus. Predicted to be part of Set1C/COMPASS complex. Is expressed in eye; long double cone cell; retinal cone cell; and retinal photoreceptor layer. Orthologous to human CXXC1 (CXXC finger protein 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

6 figures from 4 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:55527 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 4 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With cxxc1b Human Ortholog

No data available

Associated With cxxc1b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR019786	Zinc finger, PHD-type, conserved site
Domain	IPR001965	Zinc finger, PHD-type
Domain	IPR002857	Zinc finger, CXXC-type
Domain	IPR019787	Zinc finger, PHD-finger
Domain	IPR022056	CpG binding protein, C-terminal
Family	IPR037869	Spp1/CFP1
Homologous_superfamily	IPR011011	Zinc finger, FYVE/PHD-type
Homologous_superfamily	IPR013083	Zinc finger, RING/FYVE/PHD-type