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ZIRC
ZFIN ID: ZDB-GENE-990706-8
Gene Name: GLI family zinc finger 2a
Gene Symbol: gli2a
Sequence Ontology ID : SO:0001217

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Previous Names: gli2, etID12892.9 (1), fc85b05, wu:fc85b05 (1), yot, you too, you-too

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(Including Attributions)
Location: Chr: 9 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits sequence-specific DNA binding activity. Involved in several processes, including animal organ development; nervous system development; and regionalization. Localizes to the non-motile cilium  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
gli2a_unspecified Unspecified Unknown Unknown
i275 Small Deletion Unknown Unknown ZINC_FINGER_NUCLEASE
i276 Insertion Unknown Frameshift, Premature Stop ZINC_FINGER_NUCLEASE
la016571Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • s406 Unknown Unknown Unknown ENU
    sa10919 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa12847 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa15237 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa15798 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21538 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21539 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21540 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41479 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • ty17a Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • ty119 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: 44 figures from 27 publications
    Observed in:
    DISEASE ASSOCIATED WITH gli2a HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Culler-Jones syndrome Culler-Jones syndrome 615849
    holoprosencephaly 9 Holoprosencephaly 9 610829
    DISEASE ASSOCIATED WITH gli2a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process smoothened signaling pathway (more)
    Cellular Component non-motile cilium (more)
    Molecular Function sequence-specific DNA binding (more)
    GO Terms (all 33)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR013087 (1)
  • InterPro:IPR036236 (1)
  • PROSITE:PS00028 (1)
  • PROSITE:PS50157 (1)
  • Pfam:PF00096 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA gli2a-201 (1) 6039
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIES
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM gli2a
    MARKER RELATIONSHIPS
    gli2a Contained in: [BAC] CH211-61D13 (1) (order this), DKEY-25L23 (1) (order this)
    gli2a Encodes: [EST] eu801 (1), fc85b05 (1)
    [cDNA] MGC:195099 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_130967 (1) 6070 bp
    Genomic GenBank:BX548071 (1) 223099 bp Blast at MegaBLAST
    Polypeptide UniProtKB:A0A2R8QMX9 (1) 1443 aa
    Sequence Clusters UniGene:8091 (1)
    Sequence Information (all 23)
    ORTHOLOGY for gli2a ( Chr: 9 )
    CITATIONS (159)