Gene
gli2a
- ID
- ZDB-GENE-990706-8
- Name
- GLI family zinc finger 2a
- Symbol
- gli2a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Exhibits sequence-specific DNA binding activity. Involved in several processes, including animal organ development; nervous system development; and regionalization. Localizes to non-motile cilium and nucleus. Human ortholog(s) of this gene implicated in Culler-Jones syndrome; holoprosencephaly 9; and spina bifida. Is expressed in several structures, including central nervous system; digestive system; head; mesoderm; and neural plate. Orthologous to human GLI2 (GLI family zinc finger 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 33 figures from 24 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu801 (22 images)
Wild Type Expression Summary
- All Phenotype Data
- 47 figures from 29 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Culler-Jones syndrome | Alliance | Culler-Jones syndrome | 615849 |
| holoprosencephaly 9 | Alliance | Holoprosencephaly 9 | 610829 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | C2H2-type zinc-finger protein GLI-like | Zinc finger C2H2 superfamily | Zinc finger C2H2-type |
|---|---|---|---|---|
|
UniProtKB:Q9YGS4
|
1439 |
Interactions and Pathways
Plasmids
No data available