Gene

clocka

ID
ZDB-GENE-990630-14
Name
clock circadian regulator a
Symbol
clocka Nomenclature History
Previous Names
  • clk1 (1)
  • Clock1a (1)
  • clock
  • zCLOCK1 (1)
  • zfCLOCK1 (1)
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Enables DNA-binding transcription factor activity, RNA polymerase II-specific. Contributes to DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including photoperiodism; primitive hemopoiesis; and regulation of gene expression. Located in chromatin. Part of transcription regulator complex. Is expressed in brain; head; ovary; and photoreceptor cell. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human CLOCK (clock circadian regulator).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
18 figures from 13 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
6 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With clocka Human Ortholog
No data available
Associated With clocka Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000014 PAS domain
Domain IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain
Domain IPR013767 PAS fold
Family IPR001067 Nuclear translocator
Homologous_superfamily IPR035965 PAS domain superfamily
Homologous_superfamily IPR036638 Helix-loop-helix DNA-binding domain superfamily
Repeat IPR001610 PAC motif
Domain Details Per Protein
Protein Length Helix-loop-helix DNA-binding domain superfamily Myc-type, basic helix-loop-helix (bHLH) domain Nuclear translocator PAC motif PAS domain PAS domain superfamily PAS fold
UniProtKB:Q5RIV1 892
UniProtKB:Q9W6J4 893
UniProtKB:B3DIT6 892
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-clock polyclonal IgG Goat
  • IHC
  • WB
Santa Cruz Biotechnology, Inc.
3
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations